[HTML][HTML] A review of Duhuo Jisheng decoction mechanisms in intervertebral disc degeneration in vitro and animal studies

D Zhou, C Song, Y Mei, K Cheng, F Liu, W Cai… - Journal of Orthopaedic …, 2023 - Springer
Intervertebral disc degeneration (IVDD) has become a serious public health problem,
placing a heavy burden on society and the healthcare system. Its pathogenesis is not …

The Role of the Gut Microbiome in Orthopedic Surgery—a Narrative Review

DM Hiltzik, AM Goodwin, SS Kurapaty, JE Inglis… - Current Reviews in …, 2024 - Springer
Abstract Purpose of Review The importance of the gut microbiome has received increasing
attention in recent years. New literature has revealed significant associations between gut …

[HTML][HTML] Gut microbiota and intervertebral disc degeneration: a bidirectional two-sample Mendelian randomization study

Z Geng, J Wang, G Chen, J Liu, J Lan, Z Zhang… - Journal of Orthopaedic …, 2023 - Springer
Background Although previous studies have suggested a close association between gut
microbiota (GM) and intervertebral disc degeneration (IVDD), the causal relationship …

[HTML][HTML] Genetic analysis of the causal relationship between gut microbiota and intervertebral disc degeneration: a two-sample Mendelian randomized study

D Zheng, Z Wu, L Li, S Cheng, J Chang - European Spine Journal, 2023 - Springer
Purpose Several recent studies have reported a possible association between gut
microbiota and intervertebral disc degeneration; however, no studies have shown a causal …

[HTML][HTML] Changes in the composition of the fecal metabolome and gut microbiota contribute to intervertebral disk degeneration in a rabbit model

S Cheng, J Yu, M Cui, H Su, Y Cao - Journal of Orthopaedic Surgery and …, 2024 - Springer
Purpose Lower back pain (LBP), mainly caused by intervertebral disk (IVD) degeneration
(IDD), is widely prevalent worldwide and is a serious socioeconomic burden. Numerous …

[HTML][HTML] Genetically predicted causal effects of gut microbiota on spinal pain: a two-sample Mendelian randomization analysis

S Hong, L Chen, X Zhou, Y Huang, Y Tian… - Frontiers in …, 2024 - frontiersin.org
Background Observational studies have hinted at a correlation between the gut microbiota
and spinal pain (SP). However, the impact of the gut microbiota on SP remains inconclusive …

METTL3 promotes nucleus pulposus cell senescence in intervertebral disc degeneration by regulating TLR2 m6A methylation and gut microbiota

S Ni, X Huang, X Li, C Shi, M Fan, L Zhao… - The Journals of …, 2024 - academic.oup.com
Background Nucleus pulposus cell (NPC) senescence in intervertebral disc (IVD) tissue is
the major pathological cause during intervertebral disc degeneration (IDD). N6 …

The Sanbi Decoction alleviates intervertebral disc degeneration in rats through intestinal flora and serum metabolic homeostasis modulation

N Wang, S Chen, Y Xie, X Liu, Z Xi, J Li, C Xue, R Deng… - Phytomedicine, 2024 - Elsevier
Background Intervertebral disc degeneration (IVDD) is an essential cause of low back pain
(LBP), the incidence of which has risen in recent years and is progressively younger, but …

[HTML][HTML] Analysis of Intestinal Bacterial Microbiota in Individuals with and without Chronic Low Back Pain

AM Tieppo, JS Tieppo, LA Rivetti - Current Issues in Molecular Biology, 2024 - mdpi.com
Low back pain is a health problem that represents the greatest cause of years lived with
disability. This research seeks to evaluate the bacterial composition of the intestinal …

[HTML][HTML] Stop Gut Inflammation with Electroacupuncture–A Guide

A Jimenez - sciatica.clinic
When it comes to the body, the gut system has a very interesting relationship to the various
body groups. The gut system works with the central nervous, immune, and musculoskeletal …