[HTML][HTML] Different treatment strategies and molecular features between right-sided and left-sided colon cancers
H Shen, J Yang, Q Huang, MJ Jiang… - World journal of …, 2015 - ncbi.nlm.nih.gov
The colon is derived from the embryological midgut and hindgut separately, with the right
colon and left colon having different features with regards to both anatomical and …
colon and left colon having different features with regards to both anatomical and …
Genetic and epigenetic dependencies in colorectal cancer development
S Parmar, H Easwaran - Gastroenterology Report, 2022 - academic.oup.com
Recent studies have mapped key genetic changes in colorectal cancer (CRC) that impact
important pathways contributing to the multistep models for CRC initiation and development …
important pathways contributing to the multistep models for CRC initiation and development …
[HTML][HTML] Right and left-sided colon cancers-specificity of molecular mechanisms in tumorigenesis and progression
K Mukund, N Syulyukina, S Ramamoorthy… - BMC cancer, 2020 - Springer
Background Given the differences in embryonic origin, vascular and nervous supplies,
microbiotic burden, and main physiological functions of left and right colons, tumor location …
microbiotic burden, and main physiological functions of left and right colons, tumor location …
Transcription factor expression repertoire basis for epigenetic and transcriptional subtypes of colorectal cancers
YR Bhandari, V Krishna, R Powers… - Proceedings of the …, 2023 - National Acad Sciences
Colorectal cancers (CRCs) form a heterogenous group classified into epigenetic and
transcriptional subtypes. The basis for the epigenetic subtypes, exemplified by varying …
transcriptional subtypes. The basis for the epigenetic subtypes, exemplified by varying …
[HTML][HTML] Cell-of-origin DNA methylation signatures are maintained during colorectal carcinogenesis
F Bormann, M Rodríguez-Paredes, F Lasitschka… - Cell reports, 2018 - cell.com
Colorectal adenomas are precursor lesions of colorectal cancers and represent clonal
amplifications of single cells from colonic crypts. DNA methylation patterns specify cell-type …
amplifications of single cells from colonic crypts. DNA methylation patterns specify cell-type …
[HTML][HTML] Characterisation of ethnic differences in DNA methylation between UK-resident South Asians and Europeans
HR Elliott, K Burrows, JL Min, T Tillin, D Mason… - Clinical …, 2022 - Springer
Ethnic differences in non-communicable disease risk have been described between
individuals of South Asian and European ethnicity that are only partially explained by …
individuals of South Asian and European ethnicity that are only partially explained by …
[HTML][HTML] Expression changes of cell‑cell adhesion‑related genes in colorectal tumors
M Bujko, P Kober, M Mikula, M Ligaj… - Oncology …, 2015 - spandidos-publications.com
Epithelial tissues achieve a highly organized structure due to cell‑cell junction complexes.
Carcinogenesis is accompanied by changes in cell interactions and tissue morphology …
Carcinogenesis is accompanied by changes in cell interactions and tissue morphology …
Multi-omics approach reveals distinct differences in left-and right-sided colon cancer
W Hu, Y Yang, X Li, M Huang, F Xu, W Ge… - Molecular Cancer …, 2018 - AACR
Increasing evidence suggests that left-sided colon cancer (LCC) and right-sided colon
cancer (RCC) are emerging as two different colorectal cancer types with distinct clinical …
cancer (RCC) are emerging as two different colorectal cancer types with distinct clinical …
[HTML][HTML] DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer
Background Ductal carcinoma in situ (DCIS) is a heterogeneous, pre-invasive lesion
associated with an increased risk for future invasive ductal carcinoma. However, accurate …
associated with an increased risk for future invasive ductal carcinoma. However, accurate …
Molecular diagnostics in colorectal carcinoma: advances and applications for 2018
A Bhalla, M Zulfiqar, MH Bluth - Clinics in laboratory …, 2018 - labmed.theclinics.com
The pathogenesis of colorectal carcinoma is heterogeneous and involves complex multistep
molecular pathways initiated by genetic and epigenetic events. The molecular classification …
molecular pathways initiated by genetic and epigenetic events. The molecular classification …