Endometrial cancer (EC) is the 2nd common cancer in females after breast cancer. Besides,
it's the most common among gynecological cancers. Several epigenetic factors such as …

Head and neck squamous cell carcinomas (HNSCCs) arise in the mucosal linings of the
upper aerodigestive tract and are unexpectedly heterogeneous in nature. Classical risk …

Background The four major RNA adenosine modifications, ie, m 6 A, m 1 A, alternative
polyadenylation, and adenosine-to-inosine RNA editing, are mediated mostly by the “writer” …

Carcinogenesis cannot be explained only by genetic alterations, but also involves
epigenetic processes. Modification of histones by acetylation plays a key role in epigenetic …

The klotho gene encodes a type I single-pass transmembrane protein that contains a large
extracellular domain, a membrane spanning segment, and a short intracellular domain …

Epigenetic alteration has been proposed to give rise to numerous classic hallmarks of
cancer. Impaired DNA methylation plays a central role in the onset and progression of …

Cancer is one of the most complex and systemic diseases affecting the health of mankind,
causing major deaths with a significant increase. This pathology is caused by several risk …

Objectives: Breast cancer has been the second most prevalent and fatal malignancy due to
its frequent metastasis to other organs. We aim to study the effects of a key miRNA-mRNA …

Histone methylation, one of the most prominent epigenetic modifications, plays a vital role in
gene transcription, and aberrant histone methylation levels cause tumorigenesis. Histone …

Transforming growth factor‐β (TGF‐β) is a pleiotropic factor that acts as a tumor suppressor
in the early stages, while it exerts tumor promoting activities in advanced stages of cancer …