Prostate cancer is unique compared to other major cancers due to the presence of multiple
primary malignant foci in the majority of patients at the time of diagnosis. Each malignant …

Tumor endothelial cells (TECs) reside in the inner lining of blood vessels and represent a
promising target for targeted cancer therapy. DNA methylation is a chemical process that …

Brain metastasis from lung cancer is a prevalent mode of treatment failure associated with a
poor prognosis. The incidence of brain metastasis has recently shown a dramatic increase …

Abstract Enhancer of Zeste Homolog 1 (EZH1) and Enhancer of Zeste Homolog 2 (EZH2)
are the key components of polycomb repressive complex 2 (PRC2); however, the roles of …

Background Treatment failure following androgen deprivation therapy (ADT) presents a
significant challenge in the management of advanced prostate cancer. Thus, understanding …

Background Ependymoma is a central nervous system (CNS) tumor that arises from the
ependymal cells of the brain's ventricles and spinal cord. The histopathology of …

随着科技的进步, 机器人辅助腹腔镜根治性前列腺切除术逐渐变成局限性前列腺癌的重要治疗
策略, 而且可以更好地实现“长期肿瘤控制, 尿控恢复, 术后切缘阴性, 勃起功能保留 …

DNA 甲基化修饰是一种表观遗传现象, 几乎伴随着肿瘤的发生, 发展和治疗的全过程. 因此,
检测肿瘤甲基化标志物对肿瘤筛查, 诊断和监测具有重要意义. 随着甲基化检测手段和数据分析 …

本文报道了1 例临床上罕见的前列腺癌肾脏转移病例. 67 岁男性患者, 体检发现总前列腺特异性
抗原(totalprostatespecificantigen, tPSA) 升高, 为19.7 ng/mL, 游离前列腺特异性抗原 …

A rare case of renal metastasis from prostate cancer was reported. A 67-year-old male
patient was diagnosed with prostate cancer by prostate biopsy. His tPSA was 19.7 ng/mL …