Acute glomerulonephritis

S Sethi, AS De Vriese, FC Fervenza - The Lancet, 2022 - thelancet.com
Glomerulonephritis is a heterogeneous group of disorders that present with a combination of
haematuria, proteinuria, hypertension, and reduction in kidney function to a variable degree …

Standardized classification and reporting of glomerulonephritis

S Sethi, FC Fervenza - Nephrology Dialysis Transplantation, 2019 - academic.oup.com
A kidney biopsy is done to determine the etiology of the glomerulonephritis (GN) and the
severity of the lesion, to identify whether other lesions, related to or not related to the GN, are …

Pathophysiology and management of monoclonal gammopathy of renal significance

A Jain, R Haynes, J Kothari, A Khera, M Soares… - Blood …, 2019 - ashpublications.org
Recent years have witnessed a rapid growth in our understanding of the pathogenic
property of monoclonal proteins. It is evident that some of these small monoclonal proteins …

Monoclonal gammopathy of renal significance (MGRS): Real‐world data on outcomes and prognostic factors

A Gozzetti, A Guarnieri, E Zamagni… - American Journal of …, 2022 - Wiley Online Library
Monoclonal gammopathy of renal significance (MGRS) is a recognized clinical entity.
Literature regarding treatment and its outcomes in MGRS is sparse due to the rarity and …

[HTML][HTML] Light chain only variant of proliferative glomerulonephritis with monoclonal immunoglobulin deposits is associated with a high detection rate of the pathogenic …

SH Nasr, CP Larsen, C Sirac, JD Theis, C Domenger… - Kidney international, 2020 - Elsevier
IgG (mainly IgG3) is the most commonly involved isotype in proliferative glomerulonephritis
with monoclonal immunoglobulin deposits (PGNMID). Here we describe the first series of …

From patterns to proteins: mass spectrometry comes of age in glomerular disease

S Sethi, JD Theis, LMP Palma… - Journal of the American …, 2024 - journals.lww.com
Laser capture microdissection and mass spectrometry (LCM/MS) is a technique that involves
dissection of glomeruli from paraffin-embedded biopsy tissue, followed by digestion of the …

Immunotactoid glomerulopathy is a rare entity with monoclonal and polyclonal variants

SH Nasr, SS Kudose, SM Said, D Santoriello… - Kidney international, 2021 - Elsevier
Immunotactoid glomerulopathy (ITG) is a rare form of glomerulonephritis for which our
understanding is limited to case reports and small case series. Herein we describe the …

[HTML][HTML] Proteomic analysis of complement proteins in glomerular diseases

S Sethi, LMP Palma, JD Theis, FC Fervenza - Kidney International Reports, 2023 - Elsevier
Introduction Complement plays an important role in the pathogenesis of glomerulonephritis
(GN). Even though the underlying etiology of GN might be different, complement activation …

Incidence and risk factors for acute kidney injury following autologous stem cell transplantation for multiple myeloma

AG Andronesi, AD Tanase, BM Sorohan… - Cancer …, 2019 - Wiley Online Library
Acute kidney injury (AKI) is a common complication after allogeneic stem cell
transplantation; however, its incidence and outcome in patients transplanted for multiple …

[HTML][HTML] Atypical anti-GBM disease

J Bharati, Y Yang, P Sharma, KD Jhaveri - Kidney International Reports, 2023 - Elsevier
Atypical anti-GBM disease is characterized by linear immunoglobulin G (IgG) deposition
along the glomerular basement membrane (GBM) without circulating IgG anti-GBM …