Quantification of the human painful sensory experience is an essential step in the translation
of knowledge from animal nociception to human pain. Translational models for assessment …

Chronic pain is a global problem that has reached epidemic proportions. An estimated 20%
of adults suffer from pain, and another 10% are diagnosed with chronic pain each year …

We conducted a large nationwide postal survey to estimate the prevalence of chronic pain
with or without neuropathic characteristics in the French general population. A questionnaire …

We report the first nationwide survey of the impact of neuropathic pain, as opposed to
nonneuropathic pain, on quality of life and health care utilization in the French general …

Objective Despite widespread use of colchicine, the evidence basis for oral colchicine
therapy and dosing in acute gout remains limited. The aim of this trial was to compare low …

Tissue damage, inflammation or injury of the nervous system may result in chronic
neuropathic pain characterised by increased sensitivity to painful stimuli (hyperalgesia), the …

Objective: To develop a patient-completed screening tool to help differentiate nociceptive
and neuropathic pain. Research design and methods: A multicenter study was performed for …

BACKGROUND: Neuropathic pain remains one of the most challenging pain syndromes;
under-diagnosed, poorly managed and associated with significant co-morbidity. With …

Desensitization of nociceptive sensory nerve endings is the basis for the therapeutic use of
capsaicin in neuropathic pain syndromes. This study evaluated the pharmacodynamic …

The current study was designed to evaluate therapeutic potential of systemically
administered ethanolic and aqueous extracts of saffron as well as its bioactive ingredients …