The role of epigenetics in psychological resilience

D Smeeth, S Beck, EG Karam, M Pluess - The Lancet Psychiatry, 2021 - thelancet.com
There is substantial variation in people's responses to adversity, with a considerable
proportion of individuals displaying psychological resilience. Epigenetic mechanisms are …

[HTML][HTML] Methylation Dynamics of RASSF1A and Its Impact on Cancer

G Malpeli, G Innamorati, I Decimo, M Bencivenga… - Cancers, 2019 - mdpi.com
5-methyl cytosine (5mC) is a key epigenetic mark entwined with gene expression and the
specification of cellular phenotypes. Its distribution around gene promoters sets a barrier for …

[HTML][HTML] Analysis of racial/ethnic representation in select basic and applied cancer research studies

S Guerrero, A López-Cortés, A Indacochea… - Scientific reports, 2018 - nature.com
Over the past decades, consistent studies have shown that race/ethnicity have a great
impact on cancer incidence, survival, drug response, molecular pathways and epigenetics …

[HTML][HTML] Evolutionary and functional genomics of DNA methylation in maize domestication and improvement

G Xu, J Lyu, Q Li, H Liu, D Wang, M Zhang… - Nature …, 2020 - nature.com
DNA methylation is a ubiquitous chromatin feature, present in 25% of cytosines in the maize
genome, but variation and evolution of the methylation landscape during maize …

[HTML][HTML] New insights into the genetics and epigenetics of systemic sclerosis

C Angiolilli, W Marut, M van der Kroef… - Nature Reviews …, 2018 - nature.com
Systemic sclerosis (SSc) is a severe autoimmune disease that is characterized by vascular
abnormalities, immunological alterations and fibrosis of the skin and internal organs. The …

DNA methylation signatures of depressive symptoms in middle-aged and elderly persons: meta-analysis of multiethnic epigenome-wide studies

OS Jovanova, I Nedeljkovic, D Spieler… - JAMA …, 2018 - jamanetwork.com
Importance Depressive disorders arise from a combination of genetic and environmental risk
factors. Epigenetic disruption provides a plausible mechanism through which gene …

The effects of DNA methylation on human psychology

F Kader, M Ghai, L Maharaj - Behavioural brain research, 2018 - Elsevier
DNA methylation is a fundamental epigenetic modification in the human genome; pivotal in
development, genomic imprinting, X inactivation, chromosome stability, gene expression …

[HTML][HTML] Epigenetic variability in the human oxytocin receptor (OXTR) gene: A possible pathway from early life experiences to psychopathologies

EJ Kraaijenvanger, Y He, H Spencer, AK Smith… - Neuroscience & …, 2019 - Elsevier
The human oxytocin (OXT) system is implicated in the regulation of complex social
behaviors, as well as in psychopathologies characterized by social deficits. Emerging …

A review on epigenetic inheritance of experiences in humans

M Ghai, F Kader - Biochemical Genetics, 2022 - Springer
If genetics defines the inheritance of DNA, epigenetics aims to regulate and make it
adaptable. Epigenetic alterations include DNA methylation, chromatin remodelling, post …

[HTML][HTML] Characterization of DNA methylation-based markers for human body fluid identification in forensics: a critical review

F Kader, M Ghai, AO Olaniran - International journal of legal medicine, 2020 - Springer
Body fluid identification in crime scene investigations aids in reconstruction of crime scenes.
Several studies have identified and reported differentially methylated sites (DMSs) and …