The role of epigenetics in psychological resilience
There is substantial variation in people's responses to adversity, with a considerable
proportion of individuals displaying psychological resilience. Epigenetic mechanisms are …
proportion of individuals displaying psychological resilience. Epigenetic mechanisms are …
New insights into the genetics and epigenetics of systemic sclerosis
C Angiolilli, W Marut, M van der Kroef… - Nature Reviews …, 2018 - nature.com
Systemic sclerosis (SSc) is a severe autoimmune disease that is characterized by vascular
abnormalities, immunological alterations and fibrosis of the skin and internal organs. The …
abnormalities, immunological alterations and fibrosis of the skin and internal organs. The …
Analysis of racial/ethnic representation in select basic and applied cancer research studies
Over the past decades, consistent studies have shown that race/ethnicity have a great
impact on cancer incidence, survival, drug response, molecular pathways and epigenetics …
impact on cancer incidence, survival, drug response, molecular pathways and epigenetics …
Evolutionary and functional genomics of DNA methylation in maize domestication and improvement
DNA methylation is a ubiquitous chromatin feature, present in 25% of cytosines in the maize
genome, but variation and evolution of the methylation landscape during maize …
genome, but variation and evolution of the methylation landscape during maize …
DNA methylation signatures of depressive symptoms in middle-aged and elderly persons: meta-analysis of multiethnic epigenome-wide studies
OS Jovanova, I Nedeljkovic, D Spieler… - JAMA …, 2018 - jamanetwork.com
Importance Depressive disorders arise from a combination of genetic and environmental risk
factors. Epigenetic disruption provides a plausible mechanism through which gene …
factors. Epigenetic disruption provides a plausible mechanism through which gene …
Methylation Dynamics of RASSF1A and Its Impact on Cancer
G Malpeli, G Innamorati, I Decimo, M Bencivenga… - Cancers, 2019 - mdpi.com
5-methyl cytosine (5mC) is a key epigenetic mark entwined with gene expression and the
specification of cellular phenotypes. Its distribution around gene promoters sets a barrier for …
specification of cellular phenotypes. Its distribution around gene promoters sets a barrier for …
The effects of DNA methylation on human psychology
DNA methylation is a fundamental epigenetic modification in the human genome; pivotal in
development, genomic imprinting, X inactivation, chromosome stability, gene expression …
development, genomic imprinting, X inactivation, chromosome stability, gene expression …
Considerations for reproducible omics in aging research
PP Singh, BA Benayoun - Nature aging, 2023 - nature.com
Technical advancements over the past two decades have enabled the measurement of the
panoply of molecules of cells and tissues including transcriptomes, epigenomes …
panoply of molecules of cells and tissues including transcriptomes, epigenomes …
Inheritance of paternal lifestyles and exposures through sperm DNA methylation
KW Greeson, KMS Crow, RC Edenfield… - Nature Reviews …, 2023 - nature.com
Many different lifestyle factors and chemicals present in the environment are a threat to the
reproductive tracts of humans. The potential for parental preconception exposure to alter …
reproductive tracts of humans. The potential for parental preconception exposure to alter …
[HTML][HTML] Epigenetic variability in the human oxytocin receptor (OXTR) gene: A possible pathway from early life experiences to psychopathologies
The human oxytocin (OXT) system is implicated in the regulation of complex social
behaviors, as well as in psychopathologies characterized by social deficits. Emerging …
behaviors, as well as in psychopathologies characterized by social deficits. Emerging …