Circadian rhythms disrupted by light at night and mistimed food intake alter hormonal rhythms and metabolism

OH Meléndez-Fernández, JA Liu… - International Journal of …, 2023 - mdpi.com
Availability of artificial light and light-emitting devices have altered human temporal life,
allowing 24-hour healthcare, commerce and production, and expanding social life around …

Melatonin and inflammation—Story of a double‐edged blade

R Hardeland - Journal of pineal research, 2018 - Wiley Online Library
Melatonin is an immune modulator that displays both pro‐and anti‐inflammatory properties.
Proinflammatory actions, which are well documented by many studies in isolated cells or …

Melatonin reprogramming of gut microbiota improves lipid dysmetabolism in high‐fat diet‐fed mice

J Yin, Y Li, H Han, S Chen, J Gao, G Liu… - Journal of Pineal …, 2018 - Wiley Online Library
Melatonin has been shown to improve lipid metabolism and gut microbiota communities in
animals and humans; however, it remains to know whether melatonin prevents obesity …

[HTML][HTML] Melatonin: a cutaneous perspective on its production, metabolism, and functions

AT Slominski, R Hardeland, MA Zmijewski… - Journal of Investigative …, 2018 - Elsevier
Melatonin, an evolutionarily ancient derivative of serotonin with hormonal properties, is the
main neuroendocrine secretory product of the pineal gland. Although melatonin is best …

Melatonin alleviates inflammasome‐induced pyroptosis through inhibiting NF‐κB/GSDMD signal in mice adipose tissue

Z Liu, L Gan, Y Xu, D Luo, Q Ren… - Journal of Pineal …, 2017 - Wiley Online Library
Pyroptosis is a proinflammatory form of cell death that is associated with pathogenesis of
many chronic inflammatory diseases. Melatonin is substantially reported to possess anti …

Immunoporosis: immunology of osteoporosis—role of T cells

RK Srivastava, HY Dar, PK Mishra - Frontiers in immunology, 2018 - frontiersin.org
The role of immune system in various bone pathologies, such as osteoporosis, osteoarthritis,
and rheumatoid arthritis is now well established. This had led to the emergence of a modern …

Melatonin in macrophage biology: Current understanding and future perspectives

Y Xia, S Chen, S Zeng, Y Zhao, C Zhu… - Journal of pineal …, 2019 - Wiley Online Library
Melatonin is a ubiquitous hormone found in various organisms and highly affects the
function of immune cells. In this review, we summarize the current understanding of the …

[HTML][HTML] When rhythms meet the blues: circadian interactions with the microbiota-gut-brain axis

EM Teichman, KJ O'Riordan, CGM Gahan, TG Dinan… - Cell metabolism, 2020 - cell.com
The microbiota-gut-brain axis encompasses a bidirectional mode of communication
between the microorganisms residing in our gut, and our brain function and behavior. The …

Melatonin in food allergy: Mechanism and potential therapy

H Wang, Y Yan, I Hung, C Liu, J Yin… - Journal of Pineal …, 2023 - Wiley Online Library
Food allergy affects more than 500 million people in the world, and its prevalence is
increasing at an alarming rate causing serious public health concerns; however, prevention …

T cells in osteoarthritis: alterations and beyond

Y Li, W Luo, S Zhu, G Lei - Frontiers in immunology, 2017 - frontiersin.org
Although osteoarthritis (OA) has been traditionally regarded as a non-inflammatory disease,
reports increasingly suggest that it is inflammatory, at least in certain patients. OA patients …