Early life stressors display a high universal prevalence and constitute a major public health
problem. Prolonged psychoneurobiological alterations as sequelae of early life stress (ELS) …

The generalization of fear is an adaptive, behavioral, and physiological response to the
likelihood of threat in the environment. In contrast, the overgeneralization of fear, a cardinal …

Trauma-related disorders are debilitating psychiatric conditions that affect people who have
directly or indirectly witnessed adversities. Experiencing multiple types of traumas appears …

Experience of early life stress (ELS) and trauma is highly prevalent in the general population
and has a high public health impact, as it can trigger a health-related risk cascade and lead …

Increasing evidence indicates that inflammation plays a role in PTSD and stress disorder
pathophysiology. PTSD is consistently associated with higher circulating inflammatory …

Although genetics determines endocrine phenotypes, it cannot fully explain the great
variability and reversibility of the system in response to environmental changes. Evidence …

Exposure to trauma is one of the most important and prevalent risk factors for mental and
physical ill-health. Excessive or prolonged stress exposure increases the risk of a wide …

Objective Brain‐derived neurotrophic factor (BDNF) plays a crucial role in modulating
resilience and vulnerability to stress. The aim of this study was to investigate whether …

Animal models of posttraumatic stress disorder are useful tools to reveal the neurobiological
basis of the vulnerability to traumatic events, and to develop new treatment strategies, as …

Genomic variation in the SKA2 gene has recently been identified as a promising suicide
biomarker. In light of its role in glucocorticoid receptor transactivation, we investigated …