The role of microbiota in health and diseases is being highlighted by numerous studies
since its discovery. Depending on the localized regions, microbiota can be classified into …

The complex polymicrobial composition of human gut microbiota plays a key role in health
and disease. Lachnospiraceae belong to the core of gut microbiota, colonizing the intestinal …

The relationship between gut microbial dysbiosis and acute or chronic kidney disease
(CKD) is still unclear. Here, we show that oral administration of the probiotic Lactobacillus …

Intestinal tract is the boundary that prevents harmful molecules from invading into the
mucosal tissue, followed by systemic circulation. Intestinal permeability is an index for …

Renal fibrosis is an inevitable outcome of various manifestations of progressive chronic
kidney diseases (CKD). The need for efficacious treatment regimen against renal fibrosis …

Environmental changes can induce diversity shifts within ecosystems that affect interactions
between species. Similarly, the development of kidney disease induces shifts within the …

Trimethylamine-N-oxide (TMAO) is generated in a microbial-mammalian co-metabolic
pathway mainly from the digestion of meat-containing food and dietary quaternary amines …

Chronic kidney disease (CKD) afflicts more than 500 million people worldwide and is one of
the fastest growing global causes of mortality. When glomerular filtration rate begins to fall …

Background The knowledge on the mechanisms through which the metabolites produced by
the gut microbiota (postbiotics) prevent diseases, induce therapeutic responses, and behave …

Hypertension is a frequent condition encountered during kidney disease development and a
leading cause in its progression. Hallmark factors contributing to hypertension constitute a …