In recent years, a number of studies focused on the role of epigenetics, including DNA
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …

Genomic imprinting, the monoallelic and parent-of-origin-dependent expression of a subset
of genes, is required for normal development, and its disruption leads to human disease …

Cadmium is an environmental pollutant known as endocrine disruptor. Testis is particularly
susceptible to cadmium, and testis injury occurs at high but even low levels of exposure …

The past decade has seen a tremendous increase in interest and progress in the field of
sperm epigenetics. Studies have shown that chromatin regulation during male germline …

Epigenetic modifications characterized by DNA methylation, histone modifications, and
chromatin remodeling are important regulators in a number of biological processes …

The correlation between epigenetics and human reproduction represents a very interesting
field of study, mainly due to the possible transgenerational effects related to epigenetic …

OBJECTIVE: To review and summarize the current understanding of the epigenetic status of
human sperm in regards to protamination, specific localization and modifications of retained …

Background Infertility is a common reproductive disorder, with male factor infertility
accounting for approximately half of all cases. Taking a paternal perceptive, recent research …

Although male factors account for approximately 50% of all infertility, the mechanisms
underlying their origin are unknown. Currently, clinicians rely primarily on semen analyses …

Objective To evaluate whether male fertility status and/or embryo quality during in vitro
fertilization (IVF) therapy can be predicted based on genomewide sperm deoxyribonucleic …