Autism spectrum disorder: neurodevelopmental risk factors, biological mechanism, and precision therapy
L Wang, B Wang, C Wu, J Wang, M Sun - International journal of …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a heterogeneous, behaviorally defined
neurodevelopmental disorder. Over the past two decades, the prevalence of autism …
neurodevelopmental disorder. Over the past two decades, the prevalence of autism …
[HTML][HTML] Novel pharmacological targets in drug development for the treatment of anxiety and anxiety-related disorders
SB Sartori, N Singewald - Pharmacology & therapeutics, 2019 - Elsevier
Current medication for anxiety disorders is suboptimal in terms of efficiency and tolerability,
highlighting the need for improved drug treatments. In this review an overview of drugs …
highlighting the need for improved drug treatments. In this review an overview of drugs …
Cannabidiol as a potential treatment for anxiety and mood disorders: molecular targets and epigenetic insights from preclinical research
Cannabidiol (CBD) is the most abundant non-psychoactive component of cannabis; it
displays a very low affinity for cannabinoid receptors, facilitates endocannabinoid signaling …
displays a very low affinity for cannabinoid receptors, facilitates endocannabinoid signaling …
DNA methylation and schizophrenia: current literature and future perspective
T Magwai, KB Shangase, FO Oginga, B Chiliza… - Cells, 2021 - mdpi.com
Schizophrenia is a neuropsychiatric disorder characterized by dissociation of thoughts, idea,
identity, and emotions. It has no central pathophysiological mechanism and precise …
identity, and emotions. It has no central pathophysiological mechanism and precise …
Trends in big data analyses by multicenter collaborative translational research in psychiatry
The underlying pathologies of psychiatric disorders, which cause substantial personal and
social losses, remain unknown, and their elucidation is an urgent issue. To clarify the core …
social losses, remain unknown, and their elucidation is an urgent issue. To clarify the core …
Increasing Nrf2 activity as a treatment approach in neuropsychiatry
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor encoded by NFE2L2.
Under oxidative stress, Nrf2 does not undergo its normal cytoplasmic degradation but …
Under oxidative stress, Nrf2 does not undergo its normal cytoplasmic degradation but …
Exploiting circulating MicroRNAs as biomarkers in psychiatric disorders
B Roy, Y Yoshino, L Allen, K Prall, G Schell… - Molecular diagnosis & …, 2020 - Springer
Non-invasive peripheral biomarkers play a significant role in both disease diagnosis and
progression. In the past few years, microRNA (miRNA) expression changes in circulating …
progression. In the past few years, microRNA (miRNA) expression changes in circulating …
[HTML][HTML] Chromosomal and environmental contributions to sex differences in the vulnerability to neurological and neuropsychiatric disorders: Implications for …
PN Pallier, M Ferrara, F Romagnolo, MT Ferretti… - Progress in …, 2022 - Elsevier
Neurological and neuropsychiatric disorders affect men and women differently. Multiple
sclerosis, Alzheimer's disease, anxiety disorders, depression, meningiomas and late-onset …
sclerosis, Alzheimer's disease, anxiety disorders, depression, meningiomas and late-onset …
[HTML][HTML] Genetic and epigenetic factors associated with depression: An updated overview
DS Alshaya - Saudi journal of biological sciences, 2022 - Elsevier
Depression is a complex psychiatric disturbance involving many environmental, genetic,
and epigenetic factors. Until now, genetic, and non-genetic studies are still on the way to …
and epigenetic factors. Until now, genetic, and non-genetic studies are still on the way to …
Polyphenols as adjunctive treatments in psychiatric and neurodegenerative disorders: Efficacy, mechanisms of action, and factors influencing inter-individual …
The pathophysiology of psychiatric and neurodegenerative disorders is complex and
multifactorial. Polyphenols possess a range of potentially beneficial mechanisms of action …
multifactorial. Polyphenols possess a range of potentially beneficial mechanisms of action …