High WSS or low WSS? Complex interactions of hemodynamics with intracranial aneurysm initiation, growth, and rupture: toward a unifying hypothesis
Increasing detection of unruptured intracranial aneurysms, catastrophic outcomes from
subarachnoid hemorrhage, and risks and cost of treatment necessitate defining objective …
subarachnoid hemorrhage, and risks and cost of treatment necessitate defining objective …
How does hemodynamics affect rupture tissue mechanics in abdominal aortic aneurysm: Focus on wall shear stress derived parameters, time-averaged wall shear …
An abdominal aortic aneurysm (AAA) is a critical health condition with a risk of rupture,
where the diameter of the aorta enlarges more than 50% of its normal diameter. The …
where the diameter of the aorta enlarges more than 50% of its normal diameter. The …
Guidelines for the management of patients with unruptured intracranial aneurysms: a guideline for healthcare professionals from the American Heart Association …
BG Thompson, RD Brown Jr, S Amin-Hanjani… - Stroke, 2015 - Am Heart Assoc
Purpose—The aim of this updated statement is to provide comprehensive and evidence-
based recommendations for management of patients with unruptured intracranial …
based recommendations for management of patients with unruptured intracranial …
Flow conditions in the intracranial aneurysm lumen are associated with inflammation and degenerative changes of the aneurysm wall
J Cebral, E Ollikainen, BJ Chung… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Saccular intracranial aneurysm is a common disease that
may cause devastating intracranial hemorrhage. Hemodynamics, wall remodeling, and wall …
may cause devastating intracranial hemorrhage. Hemodynamics, wall remodeling, and wall …
The biophysical role of hemodynamics in the pathogenesis of cerebral aneurysm formation and rupture
The pathogenesis of intracranial aneurysms remains complex and multifactorial. While
vascular, genetic, and epidemiological factors play a role, nascent aneurysm formation is …
vascular, genetic, and epidemiological factors play a role, nascent aneurysm formation is …
Hemodynamic stress, inflammation, and intracranial aneurysm development and rupture: a systematic review
F Signorelli, S Sela, L Gesualdo, S Chevrel, F Tollet… - World neurosurgery, 2018 - Elsevier
Background There seems to be a pathogenetic link between hemodynamics and
inflammatory arterial wall alteration leading to the development and rupture of intracranial …
inflammatory arterial wall alteration leading to the development and rupture of intracranial …
Vessel wall enhancement in unruptured intracranial aneurysms: an indicator for higher risk of rupture? High-resolution MR imaging and correlated histologic findings
N Larsen, C Von Der Brelie, D Trick… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Recent studies have suggested that wall enhancement of
unruptured intracranial aneurysms in high-resolution MR imaging might serve as an imaging …
unruptured intracranial aneurysms in high-resolution MR imaging might serve as an imaging …
Difference in aneurysm characteristics between ruptured and unruptured aneurysms in patients with multiple intracranial aneurysms
D Backes, MDI Vergouwen, BK Velthuis… - Stroke, 2014 - Am Heart Assoc
Background and Purpose—Prediction of the risk of rupture of unruptured intracranial
aneurysms is mainly based on aneurysm size and location. Previous studies identified …
aneurysms is mainly based on aneurysm size and location. Previous studies identified …
CFD: computational fluid dynamics or confounding factor dissemination? The role of hemodynamics in intracranial aneurysm rupture risk assessment
Image-based computational fluid dynamics holds a prominent position in the evaluation of
intracranial aneurysms, especially as a promising tool to stratify rupture risk. Current …
intracranial aneurysms, especially as a promising tool to stratify rupture risk. Current …
Low wall shear stress is independently associated with the rupture status of middle cerebral artery aneurysms
Y Miura, F Ishida, Y Umeda, H Tanemura, H Suzuki… - Stroke, 2013 - Am Heart Assoc
Background and Purpose—We determined which hemodynamic parameter independently
characterizes the rupture status of middle cerebral artery (MCA) aneurysms using …
characterizes the rupture status of middle cerebral artery (MCA) aneurysms using …