DNA methylation in embryo development: epigenetic impact of ART (assisted reproductive technologies)
DNA methylation can be considered a component of epigenetic memory with a critical role
during embryo development, and which undergoes dramatic reprogramming after …
during embryo development, and which undergoes dramatic reprogramming after …
[HTML][HTML] Human germline cell development: from the perspective of single-cell sequencing
L Wen, F Tang - Molecular cell, 2019 - cell.com
Germline cells are the beginning of new individuals in multicellular animals, including
humans. Our understanding of these cell types is limited by the difficulty of analyzing the …
humans. Our understanding of these cell types is limited by the difficulty of analyzing the …
Single-cell DNA methylome sequencing of human preimplantation embryos
DNA methylation is a crucial layer of epigenetic regulation during mammalian embryonic
development,–. Although the DNA methylome of early human embryos has been analyzed …
development,–. Although the DNA methylome of early human embryos has been analyzed …
Live birth of chimeric monkey with high contribution from embryonic stem cells
A formal demonstration that mammalian pluripotent stem cells possess preimplantation
embryonic cell-like (naive) pluripotency is the generation of chimeric animals through early …
embryonic cell-like (naive) pluripotency is the generation of chimeric animals through early …
Dynamic epigenomic landscapes during early lineage specification in mouse embryos
In mammals, all somatic development originates from lineage segregation in early embryos.
However, the dynamics of transcriptomes and epigenomes acting in concert with initial cell …
However, the dynamics of transcriptomes and epigenomes acting in concert with initial cell …
[HTML][HTML] Inhibition of aberrant DNA re-methylation improves post-implantation development of somatic cell nuclear transfer embryos
Somatic cell nuclear transfer (SCNT) enables cloning of differentiated cells by
reprogramming their nuclei to a totipotent state. However, successful full-term development …
reprogramming their nuclei to a totipotent state. However, successful full-term development …
Genome-wide detection of imprinted differentially methylated regions using nanopore sequencing
Imprinting is a critical part of normal embryonic development in mammals, controlled by
defined parent-of-origin (PofO) differentially methylated regions (DMRs) known as imprinting …
defined parent-of-origin (PofO) differentially methylated regions (DMRs) known as imprinting …
The oviduct: from sperm selection to the epigenetic landscape of the embryo
S Pérez-Cerezales, P Ramos-Ibeas… - Biology of …, 2018 - academic.oup.com
The mammalian oviduct is the place where life begins as it is the site of fertilization and
preimplantation embryo development. Recent research has highlighted the important role …
preimplantation embryo development. Recent research has highlighted the important role …
[HTML][HTML] The epigenetics of gametes and early embryos and potential long-range consequences in livestock species—filling in the picture with epigenomic analyses
The epigenome is dynamic and forged by epigenetic mechanisms, such as DNA
methylation, histone modifications, chromatin remodeling, and non-coding RNA species …
methylation, histone modifications, chromatin remodeling, and non-coding RNA species …
[HTML][HTML] Methylome Dynamics of Bovine Gametes and in vivo Early Embryos
DNA methylation undergoes drastic fluctuation during early mammalian embryogenesis.
The dynamics of global DNA methylation in bovine embryos, however, have mostly been …
The dynamics of global DNA methylation in bovine embryos, however, have mostly been …