Major depressive disorder (MDD) is characterized by psychological and physiological
manifestations contributing to the disease severity and outcome. In recent years, several …

Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …

Epigenetics has enriched human disease studies by adding new interpretations to disease
features that cannot be explained by genetic and environmental factors. However …

Migraine is a complex, debilitating neurovascular disorder, typically characterized by
recurring, incapacitating attacks of severe headache often accompanied by nausea and …

Major depressive disorder (MDD) is a chronic disease whose neurological basis and
pathophysiology remain poorly understood. Initially, it was proposed that genetic variations …

Depression (MDD) is prodromal to, and a component of, Alzheimer's disease (AD): it may
also be a trigger for incipient AD. MDD is not a unitary disorder, so there may be particular …

There has been a limited number of systematic reviews conducted to summarize the
overview of the relationship between DNA methylation and depression, and to critically …

Abstract Major Depressive Disorder (MDD) or depression is a pathological mental condition
affecting millions of people worldwide. Identification of objective biological markers of …

Stress during sensitive developmental periods can adversely affect physical and
psychological development and contribute to later-life mental disorders. In particular …

Objective DNA methylation has been associated with both early life stress and depression.
This study examined the combined association of DNA methylation at multiple CpG probes …