Background The authors discuss the local pharmacotherapy for chronic orofacial
neuropathic pain disorders such as neuropathies, neuromas and neuralgias. Methods The …

Opioid receptors are widely expressed in the central and peripheral nervous system as well
as in numerous nonneuronal tissues. Both animal models and human clinical data support …

Painful sensory neuropathy is a common and debilitating consequence of human
immunodeficiency virus (HIV). The underlying causes of neuropathic pain are most likely not …

Opioids have long been thought to act exclusively within the central nervous system. An
increasing number of studies recently reported the existence of opioid receptors outside the …

Routine clinical assessment of health-related quality of life in persons with HIV infection has
the potential to improve care by assessing and monitoring treatment effects, enhancing …

Recent findings have suggested a significant involvement of the immune system in the
control of pain. Immune cells contain opioid peptides that are released within inflamed tissue …

Classically, pain sensation or suppression has been attributed exclusively to neuronal
circuits. This review challenges this notion and presents an expanded concept about the …

To study the prevalence, intensity, and quality of pain in patients with human
immunodeficiency virus (HIV) infection and to evaluate factors influencing the different …

The acquired immune deficiency syndrome has reached pandemic proportions.
Anaesthetists should be aware of the implications of dealing with increasing numbers of …

This prospective, open-label, before-after trial was designed to compare the efficacy of oral
opioids with that of transdermal fentanyl in severe AIDS-related chronic pain, as well as …