Haemolytic uraemic syndrome is a form of thrombotic microangiopathy affecting
predominantly the kidney and characterised by a triad of thrombocytopenia, mechanical …

Thrombotic microangiopathy can manifest in a diverse range of diseases and is
characterized by thrombocytopenia, microangiopathic hemolytic anemia, and organ injury …

Adeno-associated virus (AAV) gene therapies are highly promising, such as the
onasemnogene abeparvovec (Zolgensma) in spinal muscle atrophy (SMA). We report the …

Studies of complement genetics have changed the landscape of thrombotic
microangiopathies (TMAs), particularly atypical haemolytic uraemic syndrome (aHUS) …

Transplantation-associated thrombotic microangiopathy (TA-TMA) is an increasingly
recognized complication of hematopoietic cell transplantation (HCT) associated with …

Thrombotic microangiopathy (TMA), a pathological lesion observed in a wide spectrum of
diseases, is triggered by endothelial injury and/or dysfunction. Although TMA lesions are …

Thrombotic microangiopathy (TMA) is a condition characterized by thrombocytopenia and
microangiopathic hemolytic anemia (MAHA) with varying degrees of organ damage in the …

Complement is an elaborate system of innate immunity. Genetic variants and autoantibodies
leading to excessive complement activation are implicated in a variety of human diseases …

Human studies have shown loss of diversity of the gut microbiome following hematopoietic
stem cell transplantation (HSCT) in association with significant gut injury caused by the …

Allogeneic stem cell transplantation (alloSCT) is an effective immunotherapy in patients with
hematological malignancies. Endothelial dysfunction was linked to major complications after …