In recent years, a number of studies focused on the role of epigenetics, including DNA
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …

BACKGROUND Studies in non-human mammals suggest that environmental factors can
influence spermatozoal DNA methylation, and some research suggests that spermatozoal …

Infertility is an often devastating diagnosis encountered by around one in six couples who
are trying to conceive. Moving away from the long-held belief that infertility is primarily a …

In the last 40 years, male reproductive health—which is very sensitive to both environmental
exposure and metabolic status—has deteriorated and the poor sperm quality observed has …

Increasing interest has been attracted in deciphering the potential disease pathogenesis
through lncRNA-disease association (LDA) prediction, regarding to the diverse functional …

Polycystic ovary syndrome (PCOS) represents a serious reproductive and endocrine
condition and is associated with high incidence rates. H19 is a compelling long noncoding …

Studies on the effects of unintentional intake of pyrethroid pesticides that are akin to actual
human exposure settings are very rare. Such an exposure is primarily by consuming the …

Background and aim Aging is one of the causes of male infertility, and abnormal global DNA
methylation and imprinting defects have been characterized in testis during biological aging …

Oligozoospermia or low sperm count is a leading cause of male infertility worldwide. Despite
decades of work on non-coding RNAs (ncRNAs) as regulators of spermatogenesis …

Background Varicocoele is a common risk factor associated with reduced male fertility
potential. The current understanding of varicocoele pathophysiology does not completely …