Free radicals, antioxidant enzymes, and carcinogenesis

Y Sun - Free Radical Biology and Medicine, 1990 - Elsevier
Free radicals are found to be involved in both initiation and promotion of multistage
carcinogenesis. These highly reactive compounds can act as initiators and/or promoters …

Superoxide dismutases in malignant cells and human tumors

VL Kinnula, JD Crapo - Free Radical Biology and Medicine, 2004 - Elsevier
Reactive oxygen metabolites have multifactorial effects on the regulation of cell growth and
the capacity of malignant cells to invade. Overexpression of the superoxide dismutases …

Reactive oxygen species and antioxidant mechanisms in human tissues and their relation to malignancies

P Karihtala, Y Soini - Apmis, 2007 - Wiley Online Library
Reactive oxygen species (ROS) are formed in mammalian cells as a consequence of
aerobic respiration. Despite multiple conserved redox modulating systems, a given …

Pulmonary effects of e-liquid flavors: a systematic review

F Effah, B Taiwo, D Baines, A Bailey… - Journal of Toxicology …, 2022 - Taylor & Francis
Electronic cigarettes (ECs) are purported to be tobacco harm-reduction products whose
degree of harm has been highly debated. EC use is considered less hazardous than …

Antitumor activity and antioxidant status of Caesalpinia bonducella against Ehrlich ascites carcinoma in Swiss albino mice

M Gupta, UK Mazumder, RS Kumar… - Journal of …, 2004 - jstage.jst.go.jp
The methanol extract of Caesalpinia bonducella FLEMING (Caesalpiniaceae) leaves
(MECB) were evaluated for antitumor activity against Ehrlich ascites carcinoma (EAC) …

Pharmacologic concentrations of ascorbate are achieved by parenteral administration and exhibit antitumoral effects

J Verrax, PB Calderon - Free Radical Biology and Medicine, 2009 - Elsevier
Recently, it has been proposed that pharmacologic concentrations of ascorbate (vitamin C)
can be reached by intravenous injection. Because high doses of ascorbate have been …

Vital tooth bleaching: Biologic adverse effects—A review.

M Minoux, R Serfaty - Quintessence international, 2008 - search.ebscohost.com
Depending on etiology, the esthetic treatment of dyschromia may involve vital tooth--
bleaching techniques. Hydrogen peroxide is the active molecule used for such procedures; …

Methotrexate: pentose cycle and oxidative stress

RMV Babiak, AP Campello… - … biochemistry and its …, 1998 - Wiley Online Library
The effect of methotrexate (MTX) and leucovorin (LCV) on pentose cycle enzymes and the
activity of enzymes involved in enzyme defence mechanisms against ROS in HeLa cells …

Overexpression of human catalase inhibits proliferation and promotes apoptosis in vascular smooth muscle cells

MR Brown, FJ Miller Jr, WG Li, AN Ellingson… - Circulation …, 1999 - Am Heart Assoc
The role of reactive oxygen species, such as superoxide anions (O2·−) and hydrogen
peroxide (H2O2), in modulating vascular smooth muscle cell proliferation and viability is …

[HTML][HTML] Porphyrins, porphyrias, cancer and photodynamic therapy—a model for carcinogenesis

AMC Batlle - Journal of Photochemistry and Photobiology B: Biology, 1993 - Elsevier
Porphyrins are the only and most powerful photosensitizers synthesized internally. To
understand better the involvement of porphyrins in photosensitization reactions, the heme …