Schizophrenia is recognized to be a highly heterogeneous disease at various levels, from
genetics to clinical manifestations and treatment sensitivity. This heterogeneity is also …

Both the discovery of biomarkers of schizophrenia and the verification of biological
hypotheses of schizophrenia are an essential part of the process of understanding the …

Schizophrenia is a severe psychiatric disorder with a complex array of signs and symptoms
that causes very significant disability in young people. While schizophrenia has a strong …

Schizophrenia is a neuropsychiatric disorder characterized by dissociation of thoughts, idea,
identity, and emotions. It has no central pathophysiological mechanism and precise …

With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …

Psychopathology emerges from the dynamic interplay of physiological and mental
processes and ecological context. It can be seen as a failure of recursive, homeostatic …

Precision psychiatry has emerged as part of the shift to personalized medicine and builds on
frameworks such as the US National Institute of Mental Health Research Domain Criteria …

Epigenetic modifications are plausible molecular sources of phenotypic heterogeneity
across schizophrenia patients. The current study investigated biological heterogeneity in …

Prenatal infections have been linked to the development of schizophrenia (SCZ) and other
neurodevelopmental disorders in the offspring, and work in animal models indicates that this …

Human endogenous retroviruses (HERVs) are remnants of infections that took place several
million years ago and represent around 8% of the human genome. Despite evidence …