C3 glomerulopathy is a rare disease caused by fluid phase dysregulation of the alternative
complement pathway. Currently, treatment depends on clinical and histological severity and …

Therapy of immune-mediated kidney diseases has evolved during recent decades from the
non-specific use of corticosteroids and antiproliferative agents (like cyclophosphamide or …

Aim To contribute additional clinical experience to the paucity of reports on C3
glomerulopathy (C3GP) in children, we are reporting our cohort of 11 children with C3GP …

原发性肾病综合征(INS) 是儿童时期最常见的肾小球疾病, 频复发, 激素依赖,
激素抵抗等难治性肾病综合征仍是目前临床INS 治疗的难点, 近年来国内外陆续有文献报道利妥 …

C3 glomerulonephritis (C3GN) is a disorder of excess alternative complement activation
leading to glomerular injury. Following kidney transplantation, C3GN has a high recurrence …

Based on the results provided by electron microscopy, membranoproliferative
glomerulonephritis (MPGN) has been conventionally categorized as primary type I, type II, or …

Die membranoproliferative Glomerulonephritis (MPGN) repräsentiert eine heterogene
Gruppe von Erkrankungen. Das gemeinsame Merkmal eines membranoproliferativen …

ABSTRACT Background: C3 glomerulopathy (C3G) is an uncommon disease characterized
by the deposition of complement factors in the glomeruli due to overactivation and …

The complement system is an essential effector of innate immunity that plays a crucial role in
the defense against common pathogens and in host homeostasis. 1 Therefore, patients with …

A membranoproliferative pattern of glomerular injury is frequently observed in patients with
complement-mediated disorders, such as C3 glomerulopathies (C3G) and primary immune …