Obesity II: Establishing causal links between chemical exposures and obesity

JJ Heindel, S Howard, K Agay-Shay, JP Arrebola… - Biochemical …, 2022 - Elsevier
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

Obesity pathogenesis: an endocrine society scientific statement

MW Schwartz, RJ Seeley, LM Zeltser… - Endocrine …, 2017 - academic.oup.com
Obesity is among the most common and costly chronic disorders worldwide. Estimates
suggest that in the United States obesity affects one-third of adults, accounts for up to one …

[HTML][HTML] Potential mechanisms of bisphenol A (BPA) contributing to human disease

I Cimmino, F Fiory, G Perruolo, C Miele… - International journal of …, 2020 - mdpi.com
Bisphenol A (BPA) is an organic synthetic compound serving as a monomer to produce
polycarbonate plastic, widely used in the packaging for food and drinks, medical devices …

Early-life exposure to EDCs: role in childhood obesity and neurodevelopment

JM Braun - Nature Reviews Endocrinology, 2017 - nature.com
Endocrine-disrupting chemicals (EDCs) might increase the risk of childhood diseases by
disrupting hormone-mediated processes that are critical for growth and development during …

[HTML][HTML] An overview of epigenetics in obesity: the role of lifestyle and therapeutic interventions

AM Mahmoud - International journal of molecular sciences, 2022 - mdpi.com
Obesity has become a global epidemic that has a negative impact on population health and
the economy of nations. Genetic predispositions have been demonstrated to have a …

Endocrine disruptors and obesity

JJ Heindel, R Newbold, TT Schug - Nature Reviews Endocrinology, 2015 - nature.com
The increasing incidence of obesity is a serious global public health challenge. Although the
obesity epidemic is largely fueled by poor nutrition and lack of exercise, certain chemicals …

[HTML][HTML] Environmental obesogens and their impact on susceptibility to obesity: new mechanisms and chemicals

RJ Egusquiza, B Blumberg - Endocrinology, 2020 - academic.oup.com
The incidence of obesity has reached an all-time high, and this increase is observed
worldwide. There is a growing need to understand all the factors that contribute to obesity to …

Prenatal perfluoroalkyl substance exposure and child adiposity at 8 years of age: The HOME study

JM Braun, A Chen, ME Romano, AM Calafat… - …, 2016 - Wiley Online Library
Objective To examine relationships between prenatal perfluoroalkyl substance (PFAS)
exposure and adiposity in children born to women who lived downstream from a …

Epigenetic changes by per-and polyfluoroalkyl substances (PFAS)

S Kim, I Thapar, BW Brooks - Environmental pollution, 2021 - Elsevier
Increasing studies are examining per-and polyfluoroalkyl substances (PFAS) induced
toxicity and resulting health outcomes, including epigenetic modifications (eg, DNA …

[HTML][HTML] Application of the key characteristics of carcinogens to per and polyfluoroalkyl substances

AM Temkin, BA Hocevar, DQ Andrews… - International journal of …, 2020 - mdpi.com
Per-and polyfluoroalkyl substances (PFAS) constitute a large class of environmentally
persistent chemicals used in industrial and consumer products. Human exposure to PFAS is …