Background Mechanical ventilation is a potentially painful and discomforting intervention
that is widely used in neonatal intensive care. Newborn infants demonstrate increased …

Opioids and benzodiazepines have historically been employed for pain relief; however, they
are associated with detrimental long-term neurodevelopmental consequences …

Neonates experience significant moderate and severe postoperative pain. Effective
postoperative pain management in neonates is required to minimize acute and long-term …

The negative emotions caused by persistent pain, called affective pain, are known to
seriously affect human physical and mental health. The anterior cingulate cortex (ACC) …

Opioids for procedural pain in neonates - Kinoshita, M - 2023 | Cochrane Library Skip to
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Infants might be exposed to pain during their admissions in the neonatal intensive care unit
[NICU], both from their underlying conditions and several invasive procedures required …

Background Neonates may undergo surgery because of malformations such as
diaphragmatic hernia, gastroschisis, congenital heart disease, and hypertrophic pyloric …

Background Few studies have compared the efficacy and complications of
dexmedetomidine (DEX) and fentanyl (FEN) in extremely preterm infants. Methods We …

Background The Neonatal Pain, Agitation, and Sedation Scale (N-PASS) is a tool that, in
addition to assessing pain, also considers the level of sedation in infants. This study aimed …

Background Supporting therapies that provide stress and pain control of preterm and term
newborns infants contribute positively to the neuropsychomotor development. Non …