Regulation and function of DNA methylation in plants and animals

XJ He, T Chen, JK Zhu - Cell research, 2011 - nature.com
DNA methylation is an important epigenetic mark involved in diverse biological processes.
In plants, DNA methylation can be established through the RNA-directed DNA methylation …

Epigenetics as a unifying principle in the aetiology of complex traits and diseases

A Petronis - Nature, 2010 - nature.com
Epigenetic modifications of DNA and histones might be crucial for understanding the
molecular basis of complex phenotypes. One reason for this is that epigenetic factors are …

Epigenetic changes in cancer

K Grønbaek, C Hother, PA Jones - Apmis, 2007 - Wiley Online Library
A cancer develops when a cell acquires specific growth advantages through the stepwise
accumulation of heritable changes in gene function. Basically, this process is directed by …

[HTML][HTML] Epigenetic disturbances in in vitro cultured gametes and embryos: implications for human assisted reproduction

N El Hajj, T Haaf - Fertility and Sterility, 2013 - Elsevier
Although assisted reproductive technology (ART) has become a routine practice for human
infertility treatment, the etiology of the increased risks for perinatal problems in ART …

Epigenetic disorders and altered gene expression after use of assisted reproductive technologies in domestic cattle

R Urrego, N Rodriguez-Osorio, H Niemann - Epigenetics, 2014 - Taylor & Francis
The use of Assisted Reproductive Technologies (ARTs) in modern cattle breeding is an
important tool for improving the production of dairy and beef cattle. A frequently employed …

Cellular and molecular basis for endometriosis-associated infertility

JAW Stilley, JA Birt, KL Sharpe-Timms - Cell and tissue research, 2012 - Springer
Endometriosis is a gynecological disease characterized by the presence of endometrial
glandular epithelial and stromal cells growing in the extra-uterine environment. The disease …

In-utero stress and mode of conception: impact on regulation of imprinted genes, fetal development and future health

M Argyraki, P Damdimopoulou… - Human reproduction …, 2019 - academic.oup.com
BACKGROUND Genomic imprinting is an epigenetic gene regulatory mechanism; disruption
of this process during early embryonic development can have major consequences on both …

Epigenetic signatures of gestational diabetes mellitus on cord blood methylation

L Haertle, N El Hajj, M Dittrich, T Müller, I Nanda… - Clinical …, 2017 - Springer
Background Intrauterine exposure to gestational diabetes mellitus (GDM) confers a lifelong
increased risk for metabolic and other complex disorders to the offspring. GDM-induced …

Epigenetics and inheritance of phenotype variation in livestock

KA Triantaphyllopoulos, I Ikonomopoulos… - Epigenetics & …, 2016 - Springer
Epigenetic inheritance plays a crucial role in many biological processes, such as gene
expression in early embryo development, imprinting and the silencing of transposons. It has …

Methylation patterns in whole blood correlate with symptoms in schizophrenia patients

J Liu, J Chen, S Ehrlich, E Walton, T White… - Schizophrenia …, 2014 - academic.oup.com
DNA methylation, one of the main epigenetic mechanisms to regulate gene expression,
appears to be involved in the development of schizophrenia (SZ). In this study, we …