A proper dialogue between spermatozoa and the egg is essential for conception of a new
individual in sexually reproducing animals. Ca2+ is crucial in orchestrating this unique event …

Polycystic kidney disease (PKD) is a leading cause of ESRD worldwide. In PKD, excessive
cell proliferation and fluid secretion, pathogenic interactions of mutated epithelial cells with …

Polycystic kidney disease is a common genetic disorder in which fluid-filled cysts displace
normal renal tubules. Here we focus on autosomal dominant polycystic kidney disease …

Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic renal
disease, with an estimated prevalence between 1: 1000 and 1: 2500. It is mostly caused by …

Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic
kidney disease and is responsible for 5–10% of cases of end-stage renal disease …

Autosomal dominant polycystic kidney disease is characterized by the loss-of-function of a
signaling complex involving polycystin-1 and polycystin-2 (TRPP2, an ion channel of the …

Mutations in the polycystins PC1 or PC2 cause autosomal dominant polycystic kidney
disease (ADPKD), which is characterized by the formation of fluid-filled renal cysts that …

Animal Lectins: Form, Function and Clinical Applications presents up-to-date knowledge of
animal lectins. Detailed descriptions on biological activities, tissue and/or subcellular …

Abstract Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a systemic disorder
associated with polycystic liver disease (PLD) and other extrarenal manifestations, the most …

Abstract Mutations in polycystin-1 (PC1) and polycystin-2 (PC2) result in a commonly
occurring genetic disorder, called Autosomal Dominant Polycystic Kidney Disease (ADPKD) …