The liver possesses extraordinary regenerative capacity mainly attributable to the ability of
hepatocytes (HCs) and biliary epithelial cells (BECs) to self-replicate. This ability is left over …

Simple Summary Cholangiocarcinoma (CCA) is one of the most refractory malignancies with
a high mortality rate. Among all the pathways involved in CCA development, emerging …

Cholangiocarcinoma (CCA), a heterogeneous malignancy of bile duct epithelial cells, is
characterized by aggressiveness, difficult diagnosis, and poor prognosis due to limited …

Members of ONECUT transcription factor play an essential role in several developmental
processes, however, the atypical expression of ONECUT proteins lead to numerous …

Background: Recent researches have demonstrated that cuproptosis, a copper-dependent
cell death mechanism, is related to tumorigenesis, progression, clinical prognosis, tumor …

Abstract Swiprosin-1 or EFHD2, is a Ca 2+ binding actin protein and its expression has been
shown to be distinct in various cell types. The expression of swiprosin-1 is upregulated …

肝内胆管癌(Icc) 病因复杂, 高度侵袭, 预后不良, 是仅次于肝细胞癌的第二大肝胆恶性肿瘤.
早期手术切除仍是Icc 的最佳治疗方案, 但因其起病隐匿, 恶性程度高, 多数患者就诊时已处于中 …

RESUMO A LLA e LMA, neoplasias do sistema hematopoiético, são malignidades
hematológicas que acometem o público adulto e pediátrico, com grande comprometimento …

Intrahepatic cholangiocarcinoma (ICC) accounts for the second highest hepatobiliary
malignancy after hepatocellular carcinoma. ICC has a complex etiology and is a high …