The tree of life is split into three main branches: eukaryotes, bacteria, and archaea. Our
knowledge of eukaryotic and bacteria cell biology has been built on a foundation of studies …

The world of halophilic microorganisms is highly diverse. Microbes adapted to life at high
salt concentrations are found in all three domains of life: Archaea, Bacteria, and Eucarya. In …

Background Haloferax volcanii is an easily culturable moderate halophile that grows on
simple defined media, is readily transformable, and has a relatively stable genome. This, in …

Research into archaea will not achieve its full potential until systems are in place to carry out
genetics and biochemistry in the same species. Haloferax volcanii is widely regarded as the …

In bacteria, the tubulin homologue FtsZ assembles a cytokinetic ring, termed the Z ring, and
plays a key role in the machinery that constricts to divide the cells. Many archaea encode …

Tubulin is a major component of the eukaryotic cytoskeleton, controlling cell shape, structure
and dynamics, whereas its bacterial homologue FtsZ establishes the cytokinetic ring that …

Abstract Background Differential RNA-Seq (dRNA-Seq) is a recently developed method of
performing primary transcriptome analyses that allows for the genome-wide mapping of …

DNA replication initiates at defined sites called origins, which serve as binding sites for
initiator proteins that recruit the replicative machinery. Origins differ in number and structure …

Haloferax volcanii is an obligate halophilic archaeon with its origin in the Dead Sea. Simple
laboratory culture conditions and a wide range of genetic tools have made it a model …

Persister cells are phenotypic variants within a microbial population, which are dormant and
transiently tolerant to stress. Persistence has been studied extensively in bacteria, and in …