Emerging risk of environmental factors: insight mechanisms of Alzheimer's diseases

MA Rahman, MS Rahman, MJ Uddin… - … Science and Pollution …, 2020 - Springer
Neurodegenerative disorders are typically sporadic in nature in addition to usually
influenced through an extensive range of environmental factors, lifestyle, and genetic …

Epigenetic basis of lead-induced neurological disorders

T Wang, J Zhang, Y Xu - … journal of environmental research and public …, 2020 - mdpi.com
Environmental lead (Pb) exposure is closely associated with pathogenesis of a range of
neurological disorders, including Alzheimer's disease (AD), Parkinson's disease (PD) …

Early-life lead exposure induces long-term toxicity in the central nervous system: From zebrafish larvae to juveniles and adults

Z Wang, H Zhao, Y Xu, J Zhao, Z Song, Y Bi, Y Li… - Science of the Total …, 2022 - Elsevier
Lead induced neurotoxicity has been extensively investigated. However, the potential
connections between early-life lead exposure and the frequently observed aberrant …

Molecular mechanisms of lead neurotoxicity

MB Virgolini, M Aschner - Advances in neurotoxicology, 2021 - Elsevier
Abstract Lead (Pb 2+) is a non-essential metal with numerous industrial applications that
have led to its ubiquity in the environment. Thus, not only occupational-exposed individuals' …

Health repercussions of environmental exposure to lead: Methylation perspective

SS Shiek, MS Mani, SP Kabekkodu, HS Dsouza - Toxicology, 2021 - Elsevier
Lead (Pb) exposure has been a major public health concern for a long time now due to its
permanent adverse effects on the human body. The process of lead toxicity has still not been …

A novel aptamer-imprinted polymer-based electrochemical biosensor for the detection of lead in aquatic products

N Zhu, X Liu, K Peng, H Cao, M Yuan, T Ye, X Wu… - Molecules, 2022 - mdpi.com
Lead contamination in aquatic products is one of the main hazard factors. The aptasensor is
a promising detection method for lead ion (Pb (II)) because of its selectivity, but it is easily …

Intermittent lead exposure induces behavioral and cardiovascular alterations associated with neuroinflammation

L Shvachiy, Â Amaro-Leal, TF Outeiro, I Rocha… - Cells, 2023 - mdpi.com
The nervous system is the primary target for lead exposure and the developing brain
appears to be especially susceptible, namely the hippocampus. The mechanisms of lead …

Environmental contamination and health risk assessment to toxic elements in an active lead–zinc mining area

B Du, H Zhang, D Ji, Z Huang, G Fangqun, J Zhou - Exposure and Health, 2023 - Springer
Non-ferrous metal mining and smelting has emitted large amounts of associated toxic
elements into the environment and poses potential health risks to human health. In this …

Lead‐induced neurodevelopmental lesion and epigenetic landscape: Implication in neurological disorders

M Liu, R Liu, R Wang, Y Ba, F Yu… - Journal of Applied …, 2023 - Wiley Online Library
Lead (Pb) was implicated in multiple genotoxic, neuroepigenotoxic, and chromosomal‐toxic
mechanisms and interacted with varying synaptic plasticity pathways, likely underpinning …

Relationship between Pb relative bioavailability and bioaccessibility in phosphate amended soil: Uncertainty associated with predicting Pb immobilization efficacy …

F Kastury, S Placitu, J Boland, RR Karna… - Environment …, 2019 - Elsevier
In this study, an in vitro in vivo correlation (IVIVC) between Pb in vitro bioaccessibility (IVBA)
and relative bioavailability (RBA) was explored to determine whether the efficacy of Pb …