The Mediterranean diet (MedDiet) is one of the most widely described and evaluated dietary
patterns in scientific literature. It is characterized by high intakes of vegetables, legumes …

In this Series paper, we review trends since the 2005 Lancet Series on Neonatal Survival to
inform acceleration of progress for newborn health post-2015. On the basis of multicountry …

This review examines the current evidence for a possible connection between nutritional
intake (including micronutrients and whole diet) and neurocognitive development in …

The evidence in support of the developmental origins of the health and disease paradigm is
sufficiently robust and repeatable across species, including humans, to suggest a need for …

DNA methylation is an epigenetic mechanism that is essential for regulating gene
transcription. However, aberrant DNA methylation, which is a nearly universal finding in …

Low birth weight serves as a crude proxy for impaired growth during fetal life and indicates a
failure for the fetus to achieve its full growth potential. Low birth weight can occur in …

The function of one-carbon metabolism is that of regulating the provision of methyl groups
for biological methylation reactions including that of DNA and histone proteins. Methylation …

An association of low birth weight with an increased risk of adult cardiovascular disease and
diabetes led to the developmental origins of health and disease (DOHaD) hypothesis, which …

The recent and rapid worldwide increase in non-communicable diseases challenges the
assumption that genetic factors are the primary contributors to such diseases. A new concept …

Unlike the genome, the epigenome can be modified and hence some epigenetic risk
markers have the potential to be reversed. Such modifications take place by means of drugs …