[HTML][HTML] Tranexamic acid for the prevention and treatment of bleeding in surgery, trauma and bleeding disorders: a narrative review
A Ockerman, T Vanassche, M Garip, C Vandenbriele… - Thrombosis …, 2021 - Springer
Objectives We review the evidence for tranexamic acid (TXA) for the treatment and
prevention of bleeding caused by surgery, trauma and bleeding disorders. We highlight …
prevention of bleeding caused by surgery, trauma and bleeding disorders. We highlight …
[HTML][HTML] Tranexamic acid for haemostasis and beyond: does dose matter?
Tranexamic acid (TXA) is a widely used antifibrinolytic agent that has been used since the
1960's to reduce blood loss in various conditions. TXA is a lysine analogue that competes …
1960's to reduce blood loss in various conditions. TXA is a lysine analogue that competes …
Antifibrinolytic agents in cardiac and noncardiac surgery: a comprehensive overview and update
NS Gerstein, JK Brierley, J Windsor… - … of cardiothoracic and …, 2017 - jcvaonline.com
USING STRATEGIES TO mitigate blood loss and the need for transfusion is a fundamental
component of caring for surgical patients. Antifibrinolytic use is standard practice for complex …
component of caring for surgical patients. Antifibrinolytic use is standard practice for complex …
[HTML][HTML] Dose optimisation of intravenous tranexamic acid for elective hip and knee arthroplasty: the effectiveness of a single pre-operative dose
RJM Morrison, B Tsang, W Fishley… - Bone & Joint …, 2017 - boneandjoint.org.uk
Objectives We have increased the dose of tranexamic acid (TXA) in our enhanced total joint
recovery protocol at our institution from 15 mg/kg to 30 mg/kg (maximum 2.5 g) as a single …
recovery protocol at our institution from 15 mg/kg to 30 mg/kg (maximum 2.5 g) as a single …
Perioperative blood conservation strategies for major spine surgery
OM Theusinger, DR Spahn - Best practice & research Clinical …, 2016 - Elsevier
Background Orthopedic surgery, especially spine and spinal deformity surgery, may be
associated with high perioperative blood loss. In order to reduce the risk of excessive blood …
associated with high perioperative blood loss. In order to reduce the risk of excessive blood …
Current evidence and future directions of tranexamic acid use, efficacy, and dosing for major surgical procedures
J Taam, QJ Yang, KS Pang, P Karanicolas… - Journal of cardiothoracic …, 2020 - Elsevier
Tranexamic acid reduces blood loss and transfusion requirements with no significant
thrombotic adverse effects. Postoperative seizures have been seen in cardiac surgical …
thrombotic adverse effects. Postoperative seizures have been seen in cardiac surgical …
[HTML][HTML] The efficacy and safety of intravenous administration of tranexamic acid in patients undergoing cardiac surgery: Evidence from a single cardiovascular center
PS Lin, YT Yao, LJ Tian, JJ Jiang, Y Zhang, LX He… - Medicine, 2023 - journals.lww.com
Background: The current study was performed to systemically review the efficacy and safety
of tranexamic acid (TXA) in patients undergoing cardiac surgery at a single large-volume …
of tranexamic acid (TXA) in patients undergoing cardiac surgery at a single large-volume …
Intravenous tranexamic acid is associated with an increased risk of pulmonary embolism following sarcoma resection
D Foster, R Sebro, H Garner… - Journal of Surgical …, 2023 - Wiley Online Library
Introduction Tranexamic acid (TXA) is an antifibrinolytic drug that has been shown to reduce
blood loss following surgery. The use of TXA during orthopedic procedures has gained …
blood loss following surgery. The use of TXA during orthopedic procedures has gained …
Tranexamic acid is beneficial to patients undergoing open‐wedge high tibial osteotomy
DS Chen, JW Zhu, TF Wang, B Zhu… - BioMed Research …, 2020 - Wiley Online Library
The purpose of this study was to investigate the efficacy of tranexamic acid (TXA) in patients
undergoing open‐wedge high tibial osteotomy (OWHTO). Patients from August 2018 to May …
undergoing open‐wedge high tibial osteotomy (OWHTO). Patients from August 2018 to May …
Can high-dose tranexamic acid have a role during transurethral resection of the prostate in large prostates? A randomised controlled trial
M Samir, AM Saafan, RM Afifi, A Tawfick - Arab Journal of Urology, 2022 - Taylor & Francis
Objectives To assess the efficacy and safety of high-dose tranexamic acid (TXA) during
bipolar transurethral resection of the prostate (B-TURP) in patients with large prostates …
bipolar transurethral resection of the prostate (B-TURP) in patients with large prostates …