Objectives We review the evidence for tranexamic acid (TXA) for the treatment and
prevention of bleeding caused by surgery, trauma and bleeding disorders. We highlight …

Tranexamic acid (TXA) is a widely used antifibrinolytic agent that has been used since the
1960's to reduce blood loss in various conditions. TXA is a lysine analogue that competes …

USING STRATEGIES TO mitigate blood loss and the need for transfusion is a fundamental
component of caring for surgical patients. Antifibrinolytic use is standard practice for complex …

Objectives We have increased the dose of tranexamic acid (TXA) in our enhanced total joint
recovery protocol at our institution from 15 mg/kg to 30 mg/kg (maximum 2.5 g) as a single …

Background Orthopedic surgery, especially spine and spinal deformity surgery, may be
associated with high perioperative blood loss. In order to reduce the risk of excessive blood …

Tranexamic acid reduces blood loss and transfusion requirements with no significant
thrombotic adverse effects. Postoperative seizures have been seen in cardiac surgical …

Background: The current study was performed to systemically review the efficacy and safety
of tranexamic acid (TXA) in patients undergoing cardiac surgery at a single large-volume …

Introduction Tranexamic acid (TXA) is an antifibrinolytic drug that has been shown to reduce
blood loss following surgery. The use of TXA during orthopedic procedures has gained …

The purpose of this study was to investigate the efficacy of tranexamic acid (TXA) in patients
undergoing open‐wedge high tibial osteotomy (OWHTO). Patients from August 2018 to May …

Objectives To assess the efficacy and safety of high-dose tranexamic acid (TXA) during
bipolar transurethral resection of the prostate (B-TURP) in patients with large prostates …