Highlights•Sperm nuclear and chromatin abnormalities are common among infertile men
and are known to influence natural reproduction.•The haploid paternal genome provides the …

Infertility has become ominous problem. On an average, about 10% of all couples face
difficulty in starting a family and this creates a feeling of great personal failure, particularly in …

Objective To investigate the expression profiles of microRNA (miRNA) in human testes
showing different histopathological patterns. Design Microarray with quantitative real-time …

A total of 3179 patients were screened for Y-chromosome microdeletions and 821 patients
for partial AZFc deletions. Thirty-nine Y-chromosomal microdeletions were found (2.4% of …

Limited knowledge of the genetic causes of male infertility has resulted in few treatment and
targeted therapeutic options. Although the ideal approach to identify infertility causing …

Purpose In view of the genetic risks for the next generation, the importance of careful
evaluation of karyotypes and AZF microdeletions in male infertility prior to assisted …

Background Much interest has not been placed on the role of chromosomal abnormalities in
the pathogenesis and rising prevalence of infertility in recent times. This review was …

Objectives To determine the prevalence of Y chromosome microdeletions in infertile Korean
men with abnormal sperm counts and to assess the clinical features and frequency of …

Genetic causes can be directly responsible for various clinical conditions of male infertility
and spermatogenic impairment. With the increased use of assisted reproduction …

Infertility is defined as the inability to conceive a child after one year of regular unprotected
intercourse; it is a major health problem affecting about 10-15% of all couples. Infertility is …