Colorectal cancer is a leading cause of cancer related deaths worldwide. One of the
hallmarks of cancer and a fundamental trait of virtually all gastrointestinal cancers is …

Aging represents the multifactorial decline in physiological function of every living organism.
Over the past decades, several hallmarks of aging have been defined, including epigenetic …

ABSTRACT Gestational Diabetes Mellitus (GDM) is the most common metabolic condition
during pregnancy and may result in short-and long-term complications for both mother and …

Human cancer cell lines are an integral part of drug discovery practices. However, modeling
the complexity of cancer utilizing these cell lines on standard plastic substrata, does not …

In primary Sjögren syndrome (pSS), chronic inflammation of exocrine glands results in tissue
destruction and sicca symptoms, primarily of the mouth and eyes. Fatigue, arthralgia and …

Nonalcoholic fatty liver disease (NAFLD) is a widespread hepatic disorder in the United
States and other Westernized countries. Nonalcoholic steatohepatitis (NASH), an advanced …

In adults, reporting low and high maternal care in childhood, we compared DNA methylation
in two stress-associated genes (two target sequences in the oxytocin receptor gene, OXTR; …

Epigenetics refers to a variety of processes that have heritable effects on gene expression
programs without changes in DNA sequence. Key players in epigenetic control are chemical …

There is ample evidence that exposure to stress during gestation increases the risk of the
offspring to develop mood disorders. Brain-derived neurotrophic factor (Bdnf) plays a critical …

Epigenetics is the study of mitotically or meiotically heritable phenotypes that occur as a
result of modifications to DNA, thereby regulating gene expression independently of …