Pathogenesis and management of abdominal aortic aneurysm

J Golledge, S Thanigaimani, JT Powell… - European Heart …, 2023 - academic.oup.com
Abdominal aortic aneurysm (AAA) causes∼ 170 000 deaths annually worldwide. Most
guidelines recommend asymptomatic small AAAs (30 to< 50 mm in women; 30 to< 55 mm in …

AAA revisited: a comprehensive review of risk factors, management, and hallmarks of pathogenesis

V Kessler, J Klopf, W Eilenberg, C Neumayer… - Biomedicines, 2022 - mdpi.com
Despite declining incidence and mortality rates in many countries, the abdominal aortic
aneurysm (AAA) continues to represent a life-threatening cardiovascular condition with an …

[PDF][PDF] 2014 ESC guidelines on the diagnosis and treatment of aortic diseases

R Erbel, V Aboyans, C Boileau… - Kardiologia Polska …, 2014 - journals.viamedica.pl
Poziom B Dane pochodzące z jednej randomizowanej próby klinicznej lub dużych badań
nierandomizowanych Poziom C Uzgodniona opinia ekspertów i/lub dane pochodzące z …

Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans

JB Michel, JL Martin-Ventura, J Egido… - Cardiovascular …, 2011 - academic.oup.com
Aneurysm of the abdominal aorta (AAA) is a particular, specifically localized form of
atherothrombosis, providing a unique human model of this disease. The pathogenesis of …

Pharmacologic management of aneurysms

JH Lindeman, JS Matsumura - Circulation research, 2019 - Am Heart Assoc
Current management of aortic aneurysms relies exclusively on prophylactic operative repair
of larger aneurysms. Great potential exists for successful medical therapy that halts or …

Current status of medical management for abdominal aortic aneurysm

J Golledge, PE Norman - Atherosclerosis, 2011 - Elsevier
Previous trials indicate that surgical management of small abdominal aortic aneurysms
(AAA) does not reduce mortality. The medical management of AAA, however, has to a large …

[HTML][HTML] Thrombus volume is associated with cardiovascular events and aneurysm growth in patients who have abdominal aortic aneurysms

A Parr, M McCann, B Bradshaw, A Shahzad… - Journal of vascular …, 2011 - Elsevier
BACKGROUND:: Patients with abdominal aortic aneurysms (AAA) are predisposed to
cardiovascular events and often experience continual expansion of their aneurysm …

Platelets are at the nexus of vascular diseases

H Lebas, K Yahiaoui, R Martos… - Frontiers in cardiovascular …, 2019 - frontiersin.org
Platelets are important actors of cardiovascular diseases (CVD). Current antiplatelet drugs
that inhibit platelet aggregation have been shown to be effective in CVD treatment. However …

Antithrombotic therapy in abdominal aortic aneurysm: beneficial or detrimental?

SJ Cameron, HM Russell… - Blood, The Journal of the …, 2018 - ashpublications.org
Abdominal aortic aneurysm (AAA) is a degenerative vascular pathology resulting in
significant morbidity and mortality in older adults due to rupture and sudden death. Despite …

[HTML][HTML] D-series resolvins inhibit murine abdominal aortic aneurysm formation and increase M2 macrophage polarization

NH Pope, M Salmon, JP Davis, A Chatterjee… - The FASEB …, 2016 - ncbi.nlm.nih.gov
The role of resolvins in abdominal aortic aneurysm (AAA) has not been established. We
hypothesized that treatment with D-series resolvins (RvD2 or RvD1) would attenuate murine …