Cancer is an abnormal state of cells where they undergo uncontrolled proliferation and
produce aggressive malignancies that causes millions of deaths every year. With the new …

Metal complexes are extensively used for cancer therapy. The multiple variables available
for tuning (metal, ligand, and metal–ligand interaction) offer unique opportunities for drug …

The platinum-based drugs cisplatin, carboplatin and oxaliplatin are regularly prescribed in
the treatment of cancer and while they are effective, their use is limited by their severe, dose …

Platinum drugs have been a mainstay of cancer chemotherapy since the introduction of
cisplatin in the 1970s. Since then, carboplatin and oxaliplatin have been approved world …

Despite the extensive use of porphyrins in photodynamic therapy (PDT), tetraplatinated
porphyrins have so far not been studied for their anticancer properties. Herein, we report the …

Opioids are first-line drugs for moderate to severe acute pain and cancer pain. However,
these medications are associated with severe side effects, and whether they are efficacious …

Abstract Oxaliplatin (L-OH), a platinum derivative with good tolerability is currently combined
with Cetuximab (CTX), a monoclonal antibody (mAb), for the treatment of certain (wild-type …

Spinal glial cells contribute to the development of many types of inflammatory and
neuropathic pain. Here the contribution of spinal astrocytes and astrocyte gap junctions to …

The importance of drugs is well known, and researches on aspects of drugs have aroused
widespread concern. Molecularly imprinted polymers (MIPs) have the high affinity as well as …

Neuropathic pain is a common symptom and is associated with an impaired quality of life. It
is caused by the lesion or disease of the somatosensory system. Neuropathic pain …