Genome-wide analyses to identify biomarkers of toxicity in the treatment of advanced colorectal cancer
K Watts - 2023 - orca.cardiff.ac.uk
Background Chemotherapies administered at normal therapeutic dosages can cause
significant side-effects and may result in early treatment discontinuation. Inter-individual …
significant side-effects and may result in early treatment discontinuation. Inter-individual …
Recent developments of platinum-based anticancer drugs-detection and analysis in biological samples
P Lu, Y Li, D Hu - Current Organic Chemistry, 2015 - ingentaconnect.com
Platinum (Pt)-based pharmaceutical drugs are among the most active agents utilized for the
therapy of cancer. Carboplatin, cisplatin and oxaliplatin are three members of the platinum …
therapy of cancer. Carboplatin, cisplatin and oxaliplatin are three members of the platinum …
Participação do sistema endocanabinoide na neuromodulação da neuropatia sensitiva periférica induzida por oxaliplatina em camundongos
AF Pereira - 2020 - repositorio.ufc.br
Oxaliplatin is associated with neurotoxicity that is expressed as a peripheral sensory
neuropathy (PSN). Endocannabinoid system is known as a modulator of the nociceptive …
neuropathy (PSN). Endocannabinoid system is known as a modulator of the nociceptive …
[图书][B] Development and Validation of a High-Performance Liquid Chromatographic Method for Determination of Stability of Arsenoplatin Compounds in Saline …
K Chiem - 2023 - search.proquest.com
Arsenoplatin (AP) compounds are a new class of potent dual pharmacophore anticancer
agents that have shown efficacy in many cancers in vitro, with the most potency against …
agents that have shown efficacy in many cancers in vitro, with the most potency against …
Application of pharmacoepidemiological approaches to generate real-world evidence on the use and impact of metastatic colorectal cancer medicines
HMA Yasin - 2023 - stax.strath.ac.uk
Introduction: Metastatic colorectal cancer (mCRC) is characterised by multiple treatment
strategies. Randomised clinical trials are not always aligned with clinical practice, and …
strategies. Randomised clinical trials are not always aligned with clinical practice, and …
中西医治疗奥沙利铂神经毒性研究进展
张玮琨， 刘燕 - 湖南中医杂志, 2016 - cqvip.com
奥沙利铂是目前临床常用的抗癌药, 主要用于消化系统的恶性肿瘤, 也可治疗其他系统的癌症,
如肺癌, 卵巢癌等. 它是抗继顺铂和卡铂的第三代铂类抗肿瘤药物, 与前两代相比 …
如肺癌, 卵巢癌等. 它是抗继顺铂和卡铂的第三代铂类抗肿瘤药物, 与前两代相比 …
Chemoresistance in Colorectal Malignancies: Molecular Mechanisms and Strategies to Overcome.
Colorectal cancer (CRC) remains the third most common cause of cancer-related deaths in
both men and women worldwide. Despite recent advances in clinical practice and effective …
both men and women worldwide. Despite recent advances in clinical practice and effective …
Sol–Gel Glass and Nano–Macro Porous Bioscaffolds
To facilitate hard tissue regeneration there is a pressing need to develop biocompatible,
macroporous (pore size∼ 100's of µm) scaffolds that are tailored ideally to suit individual …
macroporous (pore size∼ 100's of µm) scaffolds that are tailored ideally to suit individual …
MAPK/ERK 通路影响人胃癌细胞对奥沙利铂敏感性的机制研究
张晔， 徐玲， 刘云鹏， 曲秀娟， 杨向红， 侯科佐， 滕月娥… - 现代肿瘤医学, 2013 - cqvip.com
目的: 探讨MAPK/ERK 通路对人胃癌细胞奥沙利铂敏感性的影响, 并进一步探讨其机制. 方法:
采用MTT 法测定奥沙利铂对人胃癌BGC823 和SGC7901 细胞的增殖抑制影响; MAPK/ERK …
采用MTT 法测定奥沙利铂对人胃癌BGC823 和SGC7901 细胞的增殖抑制影响; MAPK/ERK …
Novel potassium N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxylhex-1-yl]-l-amino acid dichloroplatinates(II) with high anti-tumor activity and low side reaction
Y Wang, G Kang, J Liu, M Zhao, J Wu, X Zhang… - Metallomics, 2012 - academic.oup.com
To discover whether novel anti-tumor platinum agents are capable of selectively
accumulating in tumor tissue, three novel potassium N-[(2 S, 3 R, 4 R, 5 R)-2, 3, 4, 5, 6 …
accumulating in tumor tissue, three novel potassium N-[(2 S, 3 R, 4 R, 5 R)-2, 3, 4, 5, 6 …