Cardiovascular disease accounts for 1 of every 2.9 deaths in the United States, thus the
burden of the disease remains high. Given the high mortality and escalating healthcare cost …

Background Screening for abdominal aortic aneurysm (AAA) in selected groups is now
performed in England, the USA and Sweden. Patients with aneurysms over 55 mm in …

Rationale: Histological examination of abdominal aortic aneurysm (AAA) tissues
demonstrates extracellular matrix destruction and infiltration of inflammatory cells. Previous …

Abdominal aortic aneurysms occur in up to 9% of adults older than 65 years of age, and the
rupture of these aneurysms accounts for about 15,000 deaths in the United States annually …

Objective—Vascular smooth muscle cell phenotypic transition plays a critical role in the
formation of abdominal aortic aneurysms (AAAs). SM22α (smooth muscle 22α) has a vital …

Objective—Abdominal aortic aneurysm (AAA) is characterized as a progressive dilation and
degradation of the aortic wall, associated with activation of matrix metalloproteinases …

OBJECTIVE: To determine whether statin therapy reduces the growth rate of small
abdominal aortic aneurysms (AAAs). DESIGN: A meta-analysis and a meta-regression of …

“Atherosclerotic” abdominal aortic aneurysms (AAAs) occur with the greatest frequency in
the distal aorta. The unique hemodynamic environment of this area predisposes it to site …

Background: Abdominal aortic aneurysm (AAA), a progressive segmental abdominal aortic
dilation, is associated with high mortality. AAA is characterized by inflammation, smooth …

Abdominal aortic aneurysm (AAA) remains a lethal aortic disease in the elderly. Currently,
no effective drugs can be clinically applied to prevent the development of AAA. Herein, a …