Hypoxia inducible factor-1α (HIF-1α) pathway is associated with many vascular diseases,
including atherosclerosis, arterial aneurysms, pulmonary hypertension and chronic venous …

Angiotensin II (AngII) is the primary bioactive peptide of the renin angiotensin system that
plays a critical role in many cardiovascular diseases. Subcutaneous infusion of AngII into …

Objective—Macrophages are critical contributors to abdominal aortic aneurysm (AAA)
disease. We examined the ability of MKEY, a peptide inhibitor of CXCL4–CCL5 interaction …

Background Management of abdominal aortic aneurysms (AAAs) relies on surgical repair of
larger AAAs. Consequently medical interventions inhibiting AAA progression could greatly …

2861 Medical Treatment for Abdominal Aortic Aneurysm ical treatments include anti-
hypertensives, statins, and antibiotics, some of which might work as MMP inhibitors. Tables …

In Europe, the prevalence of abdominal aortic aneurysms (AAAs) in the elderly population
(≥ 65 year old) has declined in the past decades to< 4%. Aneurysmal degeneration of the …

An abdominal aortic aneurysm (AAA) is an enlargement of the greatest artery in the body
defined as an increase in diameter of 1.5-fold. AAAs are common in the elderly population …

Aortic aneurysms are a complex genetic disorder with known environmental risk factors such
as smoking. Along the length of the aorta, significant heterogeneity occurs in the distribution …

Aortic aneurysm (AA) is a vascular disorder characterized pathologically by inflammatory
cell invasion and extracellular matrix (ECM) degradation. It is known that regulation of the …

Background Recent reports have showed that some statins have protective effects in
experimental cerebral aneurysm models. We conducted a case–control study to investigate …