Background Recent reports have showed that some statins have protective effects in
experimental cerebral aneurysm models. We conducted a case–control study to investigate …

An abdominal aortic aneurysm (AAA) is an enlargement of the greatest artery in the body
defined as an increase in diameter of 1.5-fold. AAAs are common in the elderly population …

Aortic aneurysms are a complex genetic disorder with known environmental risk factors such
as smoking. Along the length of the aorta, significant heterogeneity occurs in the distribution …

There is accumulating evidence that risk profiles differ between coronary artery disease and
abdominal aortic aneurysms (AAAs). However, diabetes mellitus (DM) appears to be …

Objective—Activation of inflammatory pathways plays a critical role in the development of
abdominal aortic aneurysms (AAA). Notch1 signaling is a significant regulator of the …

Granzyme B (GZMB) is a proapoptotic serine protease that is released by cytotoxic
lymphocytes. However, GZMB can also be produced by other cell types and is capable of …

Background Despite the importance of the renin-angiotensin (Ang) system in abdominal
aortic aneurysm (AAA) pathogenesis, strategies targeting this system to prevent clinical …

Abdominal aortic aneurysm (AAA) is a common aortic disease with a progressive nature.
There is no approved pharmacological treatment to effectively slow aneurysm growth or …

Abdominal aortic aneurysms (AAAs) are a multifactorial degenerative vascular disorder. One
of the defining features of the pathophysiology of aneurysmal disease is inflammation …

BACKGROUND: Despite the absence of a relationship between cholesterol and abdominal
aortic aneurysm (AAA) expansion, there is evidence from a number of studies to suggest that …