Transcription activator‐like effector (TALE) nucleases (TALENs) have recently emerged as a
revolutionary genome editing tool in many different organisms and cell types. The site …

Transposable elements (TEs) were first discovered more than 50 years ago, but were totally
ignored for a long time. Over the last few decades they have gradually attracted increasing …

Abstract DNA N 6-methyladenine (6mA) is a non-canonical DNA modification that is present
at low levels in different eukaryotes,,,,,,–, but its prevalence and genomic function in higher …

For most sequenced flowering plants, multiple whole-genome duplications (WGDs) are
found. Duplicated genes following WGD often have different fates that can quickly disappear …

Background Gene bodies are the most evolutionarily conserved targets of DNA methylation
in eukaryotes. However, the regulatory functions of gene body DNA methylation remain …

Background DNA methylation plays a key role in development, contributes to genome
stability, and may also respond to external factors supporting adaptation and evolution. To …

Endogenous retroelements, transposons that mobilize through RNA intermediates, include
some of the most abundant repetitive sequences of the human genome, such as Alu and …

DNA methyltransferases (DNMTs) are a group of proteins that catalyze DNA methylation by
transferring a methyl group to DNA. The genetic variation in DNMTs results in differential …

DNA cytosine methylation is a widely conserved epigenetic mark in eukaryotes that appears
to have critical roles in the regulation of genome structure and transcription. Genome-wide …

Background DNA methylation, which mainly occurs at CpG dinucleotides, is a dynamic
epigenetic regulation mechanism in most eukaryotic genomes. It is already known that …