DNA is the central storage molecule of genetic information in the cell, and reading that
information is a central problem in biology. While sequencing technology has made …

DNA methylation is an important epigenetic alteration that results from the covalent transfer
of a methyl group to the fifth carbon of a cytosine residue in CpG dinucleotides by DNA …

Epigenetic modifications in eukaryotic genomes occur primarily in the form of 5-
methylcytosine (5 mC). These modifications are heavily involved in transcriptional …

Methylation is an important epigenetic DNA modification that governs gene expression. The
genomic level of methylated DNA and its derivatives may serve as important indicators for …

DNA methylation is considered to be a promising marker for the early diagnosis and
prognosis of cancer. However, direct detection of the methylated DNAs in clinically relevant …

In this work, we fabricated a novel photoelectrochemical immunosensor for assay of DNA
methylation, where Bi 2 S 3 nanorods were used as photoelectric conversion material …

DNA methylation has the potential to be a clinically important biomarker in cancer. This
communication reports a real-time and label-free biosensing strategy for DNA methylation …

In this paper, we developed a novel electrochemical method to quantify DNA
methyltransferase (MTase) and analyze DNA MTase activity. After the double DNA helix …

DNA methyltransferases (MTases), a family of enzymes that catalyse the methylation of
DNA, have a profound effect on gene regulation. A large body of evidence has indicated that …

A very sensitive and convenient fluorescence nanobiosensor for rapid detection of DNA
methylation based on Fe 3 O 4/Au core/shell nanoparticles has been developed. Specific …