DNA methylation detection by a novel fluorimetric nanobiosensor for early cancer diagnosis

M Dadmehr, M Hosseini, S Hosseinkhani… - Biosensors and …, 2014 - Elsevier
A very sensitive and convenient fluorescence nanobiosensor for rapid detection of DNA
methylation based on Fe 3 O 4/Au core/shell nanoparticles has been developed. Specific …

Single base extension reaction-based surface enhanced Raman spectroscopy for DNA methylation assay

J Hu, C Zhang - Biosensors and Bioelectronics, 2012 - Elsevier
DNA methylation is a key diagnostic maker for genetic disease, cancer progression and
pharmcogenomics. So far various techniques have been developed for DNA methylation …

Optical biosensing strategies for DNA methylation analysis

MN Islam, S Yadav, MH Haque, A Munaz… - Biosensors and …, 2017 - Elsevier
DNA methylation is an epigenetic modification of DNA, where a methyl group is added at the
fifth carbon of the cytosine base to form 5 methyl cytosine (5mC) without altering the DNA …

Methylsorb: a simple method for quantifying DNA methylation using DNA–gold affinity interactions

AAI Sina, LG Carrascosa, R Palanisamy… - Analytical …, 2014 - ACS Publications
The analysis of DNA methylation is becoming increasingly important both in the clinic and
also as a research tool to unravel key epigenetic molecular mechanisms in biology. Current …

Label-free DNA-methylation detection by direct ds-DNA fragment screening using poly-purine hairpins

CS Huertas, A Aviñó, C Kurachi, A Piqué… - Biosensors and …, 2018 - Elsevier
Cancer diagnosis continuously evolves due to the better understanding of tumorigenic
processes. DNA-methylation is consolidated as an effective biomarker for cancer prognosis …

[HTML][HTML] Sensitive detection of methylated DNA and methyltransferase activity based on the lighting up of FAM-labeled DNA quenched fluorescence by gold …

MA Karimi, M Dadmehr, M Hosseini, B Korouzhdehi… - RSC …, 2019 - pubs.rsc.org
DNA methylation of cytosine bases, which is catalyzed by methyltransferase enzymes,
involve biochemical processes that contribute to gene expression and gene regulation in …

Towards DNA methylation detection using biosensors

L Syedmoradi, F Esmaeili, ML Norton - Analyst, 2016 - pubs.rsc.org
DNA methylation, a stable and heritable covalent modification which mostly occurs in the
context of a CpG dinucleotide, has great potential as a biomarker to detect disease, provide …

DNA nanotechnology in tumor liquid biopsy: Enrichment and determination of circulating biomarkers

Y Zhu, W Li, F Lan, S Chen, X Chen… - Interdisciplinary …, 2024 - Wiley Online Library
Monitoring tumor biomarkers in a non‐invasive manner for tumor diagnosis has attracted
increasing attention. Liquid biopsy mainly includes three types of biomarkers: circulating …

Label-free DNA methylation analysis using opto-fluidic ring resonators

JD Suter, DJ Howard, H Shi, CW Caldwell… - Biosensors and …, 2010 - Elsevier
The opto-fluidic ring resonator (OFRR) is a sensitive label-free optical biosensor that is
uniquely well suited for photonic and fluidic integration. For the first time we have explored …

Prospects for incorporation of epigenetic biomarkers in human health and environmental risk assessment of chemicals

G Jeremias, FJM Gonçalves, JL Pereira… - Biological …, 2020 - Wiley Online Library
Epigenetic mechanisms have gained relevance in human health and environmental studies,
due to their pivotal role in disease, gene× environment interactions and adaptation to …