DNA methylation is a major epigenetic modification in mammalian cells, and patterns
involving methylation of cytosine bases, known as CpG methylation, have been implicated in …

DNA (deoxyribonucleic acid), as the primary genetic material in eukaryotic organisms, is one
of the major biomarkers for biological processes, pathological processes and drug …

Gene‐specific promoter methylation is involved in gene silencing and is an important cancer
biomarker. Cancer‐specific methylation patterns have been observed and clinically …

The encapsulation of folded proteins in stabilizing matrices is one of the challenges of soft‐
matter materials science. Capturing such fragile bio‐macromolecules from aqueous …

Engineered proteins are very versatile tools that have been applied in assay development
for various purposes. They have been made into genetically encoded biosensors/probes or …

La presente Tesis Doctoral se centra en el desarrollo de metodologías analíticas de carácter
innovador para el estudio de diferentes rutas de regulación genética. Éstas nuevas técnicas …

Kanser, hem genetik hem de epigenetik değişikliklerin gözlendiği kalıtsal etmenlere bağlı
olduğu kadar çevresel faktörlerle de ilişkili multifaktöriyel bir hastalıktır. DNA dizisi üzerinde …

In a liquid biopsy such as blood and urine various cancer biomarkers can be measured1–3
which are secreted into body fluids by cancer cells throughout the body. 4, 5 An example of …

DNA methylation, specifically the methylation of cytosine bases, is an important biomarker,
as abnormal DNA methylation patterns are found in many different types of cancer …

This present invention provides high affinity variants of human methyl binding domain 2
(hMBD2), and nucleic acids encoding the variants, capable of recognizing and/or binding to …