The aim of this study is to provide a systematic review of the known epigenetic alterations
caused by cigarette smoke; establish an evidence-based perspective of their clinical value …

Essential hypertension (EH) is a complex, polygenic condition with no single causative
agent. Despite advances in our understanding of the pathophysiology of EH, hypertension …

Background: Alzheimer's (AD) and Parkinson's diseases (PD) show deposits of improperly
folded modified proteins. Protein expression mechanisms are involved since the early …

DNA methylation is a fundamental epigenetic modification in the human genome; pivotal in
development, genomic imprinting, X inactivation, chromosome stability, gene expression …

Background Exposure to particulate air pollution has been linked with risk of carcinogenesis.
Damage to repair pathways might have long-term adverse health effects. We aimed to …

DNA methylation of cytosine residues is a stable epigenetic alteration, beginning as early as
foetal development in the uterus and continuously evolving throughout life. DNA methylation …

Gene expression analysis plays a significant role for providing molecular insights in cancer.
Various genetic and epigenetic factors (being dealt under multi-omics) affect gene …

Placental microRNAs (miRNAs) regulate the placental transcriptome and play a pathological
role in preeclampsia (PE), a hypertensive disorder of pregnancy. Three PE rodent model …

DNA methylation (DNAm) is a fundamental biochemical modification which occurs over the
lifespan of an individual and it is a significant component in the aging process. Methylation …

Cancer metastasis is the main reason for the high mortality in patients, contributing to 90% of
cancer-related deaths. Biomarkers for early detection and therapeutic monitoring are …