Inflammatory bowel diseases (IBD) are chronic inflammatory disorders of the gastrointestinal
tract that encompass two main phenotypes, namely Crohn's disease and ulcerative colitis …

DNA is naturally dynamic and can self-assemble into alternative secondary structures
including the intercalated motif (i-motif), a four-stranded structure formed in cytosine-rich …

The epigenetic changes of RELN that are involved in the development of dopaminergic
neurons may fit the developmental theory of schizophrenia. However, evidence regarding …

Background An early onset of depression is associated with higher chronicity and disability,
more stressful life events (SLEs), higher negative emotionality as described by the primary …

Autotaxin (ATX), encoded by the ctonucleotide pyrophosphatase/phosphodiesterase 2
(ENPP2) gene, is a key enzyme in lysophosphatidic acid (LPA) synthesis. We have recently …

Prediction of complex traits using molecular genetic information is an active area in
quantitative genetics research. In the postgenomic era, many types of-omic (eg …

Epigenetic modifications are involved in global reprogramming of the cell transcriptome.
Therefore, synchronized major shifts in the expression of many genes could be achieved …

Gestational diabetes mellitus (GDM) is a maternal metabolic disorder that perturbs placental
development and increases the risk of offspring short-and long-term metabolic disorders …

Gestational diabetes mellitus (GDM) is the most prevalent metabolic disorder during
pregnancy, causing short-and long-term complications for both mother and baby. GDM is a …

Cytosine methylation in mammals is important for epigenetic control of the transcriptome.
Although altered methylation is frequently encountered in disease situations, particularly …