Novel insights into the molecular mechanisms of atherosclerosis

A Wojtasińska, W Frąk, W Lisińska, N Sapeda… - International Journal of …, 2023 - mdpi.com
Atherosclerosis is one of the most fatal diseases in the world. The associated thickening of
the arterial wall and its background and consequences make it a very composite disease …

Crosstalk between miRNAs and DNA Methylation in Cancer

M Saviana, P Le, L Micalo, D Del Valle-Morales… - Genes, 2023 - mdpi.com
miRNAs are some of the most well-characterized regulators of gene expression. Integral to
several physiological processes, their aberrant expression often drives the pathogenesis of …

[HTML][HTML] Research progress on epigenetics of diabetic cardiomyopathy in type 2 diabetes

J Deng, Y Liao, J Liu, W Liu, D Yan - Frontiers in Cell and …, 2021 - frontiersin.org
Diabetic cardiomyopathy (DCM) is characterized in its early stages by diastolic relaxation
abnormalities and later by clinical heart failure in the absence of dyslipidemia, hypertension …

Epigenetic regulation in pathology of atherosclerosis: a novel perspective

H Tang, Z Zeng, C Shang, Q Li, J Liu - Frontiers in Genetics, 2021 - frontiersin.org
Atherosclerosis, characterized by atherosclerotic plaques, is a complex pathological process
that involves different cell types and can be seen as a chronic inflammatory disease. In the …

MicroRNA‐146a serves as a biomarker for adverse prognosis of ST‐segment elevation myocardial infarction

S Xiao, T Xue, Q Pan, Y Hu, Q Wu, Q Liu… - Cardiovascular …, 2021 - Wiley Online Library
Objective. This study is aimed at exploring the underlying molecular mechanisms of ST‐
segment elevation myocardial infarction (STEMI) and provides potential clinical prognostic …

Paternal genetic intergenerational and transgenerational effects of cadmium exposure on hormone synthesis disorders in progeny ovarian granulosa cells

Y Sun, C Zhang, L Luo, H Lin, C Liu, W Zhang - Environmental Pollution, 2023 - Elsevier
To investigate the paternal genetic effects of cadmium (Cd) exposure on hormone synthesis
disorders in the ovarian granulosa cells (GCs) of offspring. Here, male Sprague‒Dawley …

Role of the microRNA-29 family in myocardial fibrosis

C Li, N Wang, P Rao, L Wang, D Lu, L Sun - Journal of physiology and …, 2021 - Springer
Myocardial fibrosis (MF) is an inevitable pathological process in the terminal stage of many
cardiovascular diseases, often leading to serious cardiac dysfunction and even death …

Identification of epigenetic interactions between MicroRNA-30c-5p and DNA methyltransferases in neuropathic pain

R Francés, J Mata-Garrido, R de la Fuente… - International Journal of …, 2022 - mdpi.com
Neuropathic pain is a prevalent and severe chronic syndrome, often refractory to treatment,
whose development and maintenance may involve epigenetic mechanisms. We previously …

Circulating miR-143 and miR-145 as promising biomarkers for evaluating severity of coronary artery stenosis in patients with acute coronary syndrome

L Meng, X Yu, H Han, X Jia, B Hu, L Zhang, Z Wang… - Clinical …, 2023 - Elsevier
Background Multiple studies have provided evidence that miR-143 and miR-145 play a
crucial role in the pathogenesis and progression of atherosclerosis. In the present study, we …

ox-LDL regulates proliferation and apoptosis in VSMCs by controlling the miR-183-5p/FOXO1

M Fan, Y Huang, K Li, X Yang, J Bai, Q Si, Z Peng… - Genes & Genomics, 2022 - Springer
Background microRNA–mRNA axes that are involved in oxidized low-density lipoprotein (ox-
LDL)-induced vascular smooth muscle cells (VSMCs) proliferation/apoptosis imbalance …