[HTML][HTML] Recognition of seven species in the Cryptococcus gattii/Cryptococcus neoformans species complex

F Hagen, K Khayhan, B Theelen, A Kolecka… - Fungal genetics and …, 2015 - Elsevier
Phylogenetic analysis of 11 genetic loci and results from many genotyping studies revealed
significant genetic diversity with the pathogenic Cryptococcus gattii/Cryptococcus …

Cryptococcus neoformans: historical curiosity to modern pathogen

D Srikanta, FH Santiago‐Tirado, TL Doering - Yeast, 2014 - Wiley Online Library
The importance of the Basidiomycete Cryptococcus neoformans to human health has
stimulated its development as an experimental model for both basic physiology and …

Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts

CA D'souza, JW Kronstad, G Taylor, R Warren, M Yuen… - MBio, 2011 - Am Soc Microbiol
Cryptococcus gattii recently emerged as the causative agent of cryptococcosis in healthy
individuals in western North America, despite previous characterization of the fungus as a …

The emerging role of extracellular vesicles in fungi: A double-edged sword

Y Lai, B Jiang, F Hou, X Huang, B Ling, H Lu… - Frontiers in …, 2023 - frontiersin.org
Fungi are eukaryotic microorganisms found in nature, which can invade the human body
and cause tissue damage, inflammatory reactions, organ dysfunctions, and diseases. These …

Animal Models of Cryptococcus neoformans in Identifying Immune Parameters Associated With Primary Infection and Reactivation of Latent Infection

TG Normile, AM Bryan, M Del Poeta - Frontiers in Immunology, 2020 - frontiersin.org
Cryptococcus species are environmental fungal pathogens and the causative agents of
cryptococcosis. Infection occurs upon inhalation of infectious particles, which proliferate in …

Dormancy in Cryptococcus neoformans: 60 years of accumulating evidence

A Alanio - The Journal of clinical investigation, 2020 - Am Soc Clin Investig
Cryptococcus neoformans is an opportunistic yeast that is present worldwide and interacts
with various organisms. In humans, it is responsible for cryptococcosis, a deadly invasive …

Adaptation of Cryptococcus neoformans to mammalian hosts: integrated regulation of metabolism and virulence

J Kronstad, S Saikia, ED Nielson, M Kretschmer… - Eukaryotic …, 2012 - Am Soc Microbiol
The basidiomycete fungus Cryptococcus neoformans infects humans via inhalation of
desiccated yeast cells or spores from the environment. In the absence of effective immune …

The tools for virulence of Cryptococcus neoformans

C Coelho, AL Bocca, A Casadevall - Advances in applied microbiology, 2014 - Elsevier
Cryptococcus neoformans is a fungal pathogen that causes almost half a million deaths
each year. It is believed that most humans are infected with C. neoformans, possibly in a …

Host-pathogen interactions mediated by MDR transporters in fungi: as pleiotropic as it gets!

M Cavalheiro, P Pais, M Galocha, MC Teixeira - Genes, 2018 - mdpi.com
Fungal infections caused by Candida, Aspergillus, and Cryptococcus species are an
increasing problem worldwide, associated with very high mortality rates. The successful …

Proteomics reveals that the antifungal activity of fenbendazole against Cryptococcus neoformans requires protein kinases

HC de Oliveira, MDM Santos… - International Journal of …, 2024 - Elsevier
Cryptococcus neoformans is responsible for over 100 000 deaths annually, and the
treatment of this fungal disease is expensive and not consistently effective. Unveiling new …