Effects and mechanisms of curcumin for the prevention and management of cancers: An updated review

ZJ Yang, SY Huang, DD Zhou, RG Xiong, CN Zhao… - Antioxidants, 2022 - mdpi.com
Cancer is the leading cause of death in the world. Curcumin is the main ingredient in
turmeric (Curcuma longa L.), and is widely used in the food industry. It shows anticancer …

[HTML][HTML] Curcumin: An epigenetic regulator and its application in cancer

T Ming, Q Tao, S Tang, H Zhao, H Yang, M Liu… - Biomedicine & …, 2022 - Elsevier
Nowadays, one of the leading causes of death in humans is cancer, which is still on the rise
globally and is in great need of intense study on the pathogenic mechanism and effective …

Molecular targets of natural compounds with anti-cancer properties

M Kubczak, A Szustka, M Rogalińska - International Journal of Molecular …, 2021 - mdpi.com
Cancer is the second leading cause of death in humans. Despite rapid developments in
diagnostic methods and therapies, metastasis and resistance to administrated drugs are the …

The role of epigenetic modifications in human cancers and the use of natural compounds as epidrugs: Mechanistic pathways and pharmacodynamic actions

A Bouyahya, H Mechchate, L Oumeslakht, I Zeouk… - Biomolecules, 2022 - mdpi.com
Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal
cells. The mechanistic understanding of the pathways involved in tumor transformation has …

Polymeric nanomicelles of curcumin: Potential applications in cancer

L Farhoudi, P Kesharwani, M Majeed… - International Journal of …, 2022 - Elsevier
Natural compounds, primarily derived from plants, have been isolated and evaluated as
alternative and complementary treatments for cancer. Curcumin has been proven to be …

Progress in natural compounds/siRNA co-delivery employing nanovehicles for cancer therapy

M Ashrafizadeh, A Zarrabi, K Hushmandi… - ACS combinatorial …, 2020 - ACS Publications
Chemotherapy using natural compounds, such as resveratrol, curcumin, paclitaxel,
docetaxel, etoposide, doxorubicin, and camptothecin, is of importance in cancer therapy …

Curcumin inhibits ovarian cancer progression by regulating circ-PLEKHM3/miR-320a/SMG1 axis

S Sun, H Fang - Journal of Ovarian Research, 2021 - Springer
Background Curcumin has a potential therapeutic role in ovarian cancer. However, whether
curcumin plays anti-cancer role in ovarian cancer by mediating the circular RNA …

Current insights into epigenetics, noncoding RNA interactome and clinical pharmacokinetics of dietary polyphenols in cancer chemoprevention

D Shah, M Gandhi, A Kumar… - Critical reviews in …, 2023 - Taylor & Francis
Several studies have reported the health-beneficial effects of dietary phytochemicals,
namely polyphenols, to prevent various diseases, including cancer. Polyphenols, like (−) …

Sensing the scent of death: Modulation of microRNAs by Curcumin in gastrointestinal cancers

M Ashrafizadeh, A Zarrabi, M Hashemipour… - Pharmacological …, 2020 - Elsevier
Gastrointestinal (GI) cancers with a high incidence rate and adverse complications are
related to severe morbidity and mortality around the world. MicroRNAs (miRs) are potential …

Curcumin in the treatment of liver cancer: from mechanisms of action to nanoformulations

SI Shelash Al‐Hawary… - Phytotherapy …, 2023 - Wiley Online Library
Liver cancer is the sixth most prevalent cancer and ranks third in cancer‐related death, after
lung and colorectal cancer. Various natural products have been discovered as alternatives …