Epithelial mesenchymal transition (EMT), the adoption by epithelial cells of a mesenchymal-
like phenotype, is a process co-opted by carcinoma cells in order to initiate invasion and …

Pdcd4 (programmed cell death 4) has been known as a tumour suppressor gene and
potential target for anticancer therapies for several years. Initially, Pdcd4 was identified as a …

Long noncoding RNAs (lncRNAs) have emerged as key regulators of tumor development
and progression. The lncRNA HNF1A-antisense 1 (HNF1A-AS1) is a 2455-bp transcript on …

The Wnt (wingless-type) signaling pathway plays an important role in embryonic
development, tissue homeostasis, and tumor progression becaluse of its effect on cell …

The hepatitis B virus (HBV) X protein (HBx) has a key role in the molecular pathogenesis of
HBV-related hepatocellular carcinoma (HCC). However, the mechanism of HBx-mediated …

Programmed cell death factor 4 (PDCD4) is originally described as a tumor suppressor gene
that exerts antineoplastic effects by promoting apoptosis and inhibiting tumor cell …

Hepatocellular carcinoma (HCC) is one of the most common causes of malignancy-related
deaths. Lenvatinib, as a multi-targeted tyrosine kinase inhibitor, has gained increasing …

Promoter hypermethylation mediated by DNA methyltransferases (DNMTs) is the main
reason for epigenetic inactivation of tumor suppressor genes (TSGs). Previous studies …

Effective detection of DNA methyltransferase (DNMT) activity is significant for cancer
research. Herein, we developed a sensitive electroanalytical method to detect human DNA …

Renal cancer metastasis may result from oncogenic forces that contribute to the primary
tumor. We have recently identified microRNA-21 as an oncogenic driver of renal cancer …