Spinal stenosis is a common degenerative spine disorder in the aged population and the
spinal ligament aging is a main contributor to this chronic disease. However, the underlying …

Background Hypertrophy of ligamentum flavum (HLF) is the mainly cause of lumbar spinal
stenosis (LSS), but the precise mechanism of HLF formation has not been fully elucidated …

Lumbar spinal stenosis (LSS), which can lead to irreversible neurologic damage and
functional disability, is characterized by hypertrophy and fibrosis in the ligamentum flavum …

Background Ligamentum flavum (LF) hypertrophy is the main cause of lumbar spinal canal
stenosis (LSCS). Previous studies have shown that LF hypertrophy tissue exhibits abnormal …

Background Increasing evidences have shown that long non-coding RNAs (lncRNAs)
display crucial regulatory roles in the occurrence and development of numerous diseases …

Abstract The Biospecimen Collection and Processing Working Group of the National
Institutes of Health (NIH) HEAL Initiative BACPAC Research Program was charged with …

Ligamentum flavum hypertrophy (LFH) is a major cause of lumbar spinal stenosis (LSS). In
hypertrophic ligamentum flavum (LF) cells, oxidative stress activates intracellular signaling …

RESUMO JUSTIFICATIVA E OBJETIVOS: Os sintomas da dor lombar são algumas das
queixas mais comuns. A epigenética representa um mecanismo pelo qual o meio pode …

ABSTRACT BACKGROUND AND OBJECTIVES: Low back pain is one of the most common
complaints. Epigenetics represents a mechanism where the environment can modify gene …

Lumbar spinal stenosis (LSS), which can lead to irreversible neurologic damage and
functional disability, is characterized by hypertrophy and fibrosis in the ligamentum flavum …